15911-16-7

Basic information

• Product Name: 3,4-DIMETHYL-6H-ISOXAZOLO[3,4-D]PYRIDAZIN-7-ONE
• Synonyms: 4-d)pyridazin-7(6h)-one,3,4-dimethyl-isoxazolo(;Isoxazolo[3,4-d]pyridazin-7(6H)-one, 3,4-dimethyl- (8CI,9CI);Isoxazolo[3,4-d]pyridazin-7(6H)-one,3,4-diMethyl-;3,4-DIMETHYLISOXAZOLO[3,4-D]PYRIDAZIN-7(6H)-ONE;3,4-DIMETHYL-6H-ISOXAZOLO[3,4-D]PYRIDAZIN-7-ONE;3,4-dimethyl-6H-[1,2]oxazolo[3,4-d]pyridazin-7-one
• CAS NO: 15911-16-7
• Molecular Formula: C₇H₇N₃O₂
• Molecular Weight: 165.15
• Product Categories: OXAZOLE
• Mol File: 15911-16-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.58g/cm³
• Refractive Index: 1.709
• CAS DataBase Reference: 3,4-DIMETHYL-6H-ISOXAZOLO[3,4-D]PYRIDAZIN-7-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIMETHYL-6H-ISOXAZOLO[3,4-D]PYRIDAZIN-7-ONE(15911-16-7)
• EPA Substance Registry System: 3,4-DIMETHYL-6H-ISOXAZOLO[3,4-D]PYRIDAZIN-7-ONE(15911-16-7)

Safety Data

• Hazardous Substances Data: 15911-16-7(Hazardous Substances Data)

Usage

Description

3,4-DIMETHYL-6H-ISOXAZOLO[3,4-D]PYRIDAZIN-7-ONE is a heterocyclic chemical compound characterized by a molecular formula of C9H8N2O. It features a pyridazine ring fused to an isoxazole ring, along with a ketone group at the 7th position. 3,4-DIMETHYL-6H-ISOXAZOLO[3,4-D]PYRIDAZIN-7-ONE is of interest in the pharmaceutical industry and medicinal chemistry due to its potential for use in the synthesis of various drugs and its possible biological activities and properties.

Uses

Used in Pharmaceutical Industry:
3,4-DIMETHYL-6H-ISOXAZOLO[3,4-D]PYRIDAZIN-7-ONE is used as a key intermediate in the synthesis of various drugs for its structural and functional versatility. Its unique heterocyclic structure allows for the development of new pharmaceutical agents with potential therapeutic applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 3,4-DIMETHYL-6H-ISOXAZOLO[3,4-D]PYRIDAZIN-7-ONE is utilized as a building block for designing and optimizing drug candidates. Its chemical properties and potential biological activities make it a valuable component in the creation of novel therapeutic agents.
Used in Drug Discovery:
3,4-DIMETHYL-6H-ISOXAZOLO[3,4-D]PYRIDAZIN-7-ONE is employed as a subject of interest for further research and development in drug discovery. Its exploration may lead to the identification of new compounds with significant biological activities, contributing to the advancement of pharmaceutical treatments.

InChI:InChI=1/C7H7N3O2/c1-3-5-4(2)12-10-6(5)7(11)9-8-3/h1-2H3,(H,9,11)

Upstream product

• 15911-11-2 ethyl 4-acetyl-5-methyl-1,2-oxazole-3-carboxylate 
• 123-54-6 acetylacetone 

Downstream Products

• 853774-68-2 4-methyl-3-[2-(4-nitro-phenyl)-vinyl]-6H-isoxazolo[3,4-d]pyridazin-7-one 
• 1258303-88-6 3,4-dimethyl-6-(1-phenylethyl)isoxazolo[3,4-d]pyridazin-7(6H)-one 
• 910315-64-9 6-benzyl-3,4-dimethylisoxazolo[3,4-d]pyridazin-7(6H)-one 
• 1192490-69-9 5-acetyl-4-amino-6-methyl-2-[3-(4-p-tolylpiperazin-1-yl)propyl]pyridazin-3(2H)-one 
• 1192490-77-9 4-amino-5-(1-hydroxyethyl)-6-methyl-2-[3-(4-p-tolylpiperazin-1-yl)propyl]pyridazin-3(2H)-one 
• 1192490-85-9 4-amino-6-methyl-2-[3-(4-p-tolylpiperazin-1-yl)propyl]-5-vinylpyridazin-3(2H)-one 

Relevant articles and documents

New pyrazolo[1′,5′:1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective PDE5 inhibitors

A series of potent PDE5 inhibitors with high selectivity versus PDE6 isoenzymes was identified.

New derivatives of the isoxazolo-(3,4-d)-pyridazin-7-one system

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