15931-59-6

Basic information

• Product Name: (DIETHYLAMINO)METHANOL
• Synonyms: (DIETHYLAMINO)METHANOL;Einecs 240-069-6;Methanol, (diethylamino)-;Methanol, 1-(diethylamino)-
• CAS NO: 15931-59-6
• Molecular Formula: C₅H₁₃NO
• Molecular Weight: 103.16
• EINECS: 240-069-6
• Mol File: 15931-59-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 129.6°Cat760mmHg
• Flash Point: 30.2°C
• Appearance: /
• Density: 0.89g/cm³
• Vapor Pressure: 4.55mmHg at 25°C
• Refractive Index: 1.439
• PKA: 14.05±0.10(Predicted)
• CAS DataBase Reference: (DIETHYLAMINO)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (DIETHYLAMINO)METHANOL(15931-59-6)
• EPA Substance Registry System: (DIETHYLAMINO)METHANOL(15931-59-6)

Safety Data

• Hazardous Substances Data: 15931-59-6(Hazardous Substances Data)

Usage

General Description

(DIETHYLAMINO)METHANOL, also known as methyldiethylamine, is a chemical compound with the formula C5H13NO. It is a colorless liquid with a fishy odor, and it is commonly used as a catalyst in the production of polyurethane foams and in the synthesis of pharmaceuticals and agrochemicals. (DIETHYLAMINO)METHANOL is also used as a solvent in chemical reactions and as a reagent in the synthesis of various organic compounds. It is considered to be a potentially hazardous chemical and should be handled with care, as it can cause irritation to the skin, eyes, and respiratory system upon exposure.

InChI:InChI=1/C5H13NO/c1-3-6(4-2)5-7/h7H,3-5H2,1-2H3

Upstream product

• 463-57-0 methanediol 
• 109-89-7 diethylamine 
• 50-00-0 formaldehyd 
• 7732-18-5 water 

Downstream Products

• 10575-26-5 1-diethylamino-pent-2-yn-4-ol 
• 1695-47-2 5-(diethylamino-methyl)-2-phenyl-[1,3]thiazine-4,6-dione 
• 1695-51-8 2-(4-chloro-phenyl)-5-(diethylamino-methyl)-[1,3]thiazine-4,6-dione 
• 1695-54-1 5-(diethylamino-methyl)-2-(3,4-dimethyl-phenyl)-[1,3]thiazine-4,6-dione 
• 1833-20-1 5-(diethylamino-methyl)-2-(4-isopropoxy-phenyl)-3H-[1,3]thiazine-4,6-dione 
• 3299-38-5 4-(diethylamino)butan-2-one 
• 121-44-8 triethylamine 
• 46721-07-7 4-amino-benzoic acid-(diethylamino-methyl ester) 
• 10196-75-5 N-[(diethylamino)methyl]-2-methylprop-2-enamide 
• 100-40-3 4-ethenylcyclohexene 
• 64596-17-4 N,N-diethylocta-2,7-dien-1-amine 
• 74067-09-7 N-2,6,8-nonatrienyldiethylamine 
• 74083-37-7 1,1-diethylamino-3,8-nonadiene 
• 463-57-0 methanediol 

Relevant articles and documents

Aminomethylation of tocopherols

A process for the production of a Mannich reagent comprises reacting formaldehyde, especially paraformaldehyde, with a secondary amine in the complete or almost complete absence of a solvent. An alternative comprises reacting a diaminomethane produced from a secondary amine, formaldehyde, especially paraformaldehyde, as well as water with one another in about equimolar amounts. The invention is also concerned with a process for the aminomethylation of δ-tocopherol or of tocopherol mixtures containing this and comprises using a Mannich reagent which has been produced in the above manner. After completion of this aminomethylation process excess Mannich reagent can be separated by distillation and can be reacted with water and formaldehyde, especially paraformaldehyde, in order to regenerate further Mannich reagent suitable for use in the aminomethylation, this regeneration representing a further aspect of the invention. Finally, the invention includes certain novel bis(aminomethyl)-γ-tocopherols.

A quick procedure for the preparation of 1-N,N-dialkylamino-1-buten-3-ynes

1-N,N-Dialkylamino-1-buten-3-ynes, HC≡CCH=CHNR2 (R = CH3 or C2H5, E/Z ratio ~97:3) have been prepared in 80 and 84% yields by treating the Mannich-coupling products from HC≡CCH2OCH3 and R2NCH2OH, CH3OCH2C≡CCH2NR2, with two equivalents of potassium amide in liquid ammonia and subsequently adding methanol or ammonium chloride.

Nitrite Ion as a Nitrosating Reagent. Nitrosation of Morpholine and Diethylamine in the Presence of Formaldehyde

The kinetics of the nitrosation of morpholine and diethylamine in the presence of formaldehyde has been studied at pH values between 6.5-8.2 and 6.9-8.7, respectively.The results are interpreted through a mechanism that implies the reaction between both the nitrite NO2(-) and iminium R2N(+)=CH2 ions.The latter ion results from the dehydration of the conjugated acid of the carbinolamine, R2NH(+)CH2OH, the initial product of the amine-formaldehyde reaction.The results allow the calculation of the equlibrium constants of the formation of carbinolamine, R2NCH2OH, and methanediamine, R2NCH2NR2 (only for the morpholine-formaldehyde system), and their conjugate acids.