159390-17-7

Upstream product

• 7596-12-5 3-methyl-4-nitrobenzophenone 
• 7439-89-6 iron 
• 72106-42-4 5-benzoyl-2-nitrobenzonitrile 
• 7501-56-6 3-chloro-4-nitrobenzophenone 
• 71-43-2 benzene 
• 122-04-3 4-nitro-benzoyl chloride 
• 1137-41-3 (4-aminophenyl)(phenyl)methanone 
• 860594-62-3 (4-amino-3-iodophenyl)(phenyl)methanone 
• 1144-74-7 4-nitrobenzophenone 
• 130344-80-8 5-Benzoyl-2-nitro-benzoyl chloride 
• 130344-78-4 5-benzoyl-2-nitrobenzoic acid 
• 130344-74-0 5-Benzoyl-2-nitro-benzamide 

Downstream Products

• 1354385-69-5 4-amino-6-benzoyl-2(1H)-quinazolinone 

Relevant academic research and scientific papers

Synthesis, molecular modelling and biological evaluation of 4-amino-2(1H)-quinazolinone and 2,4(1H,3H)-quinazolidone derivatives as antitumor agents

A series of 6-benzoyl-, 6-arylthio- and 6-arylsulfonyl-4-amino-2(1H)- quinazolinones and -2,4(1H,3H)-quinazolinediones were prepared. They were evaluated in vitro for their cytotoxicity against the NCI-60 cancer cell lines. A series of 6-benzoyl-, 6-arylthio- and 6-arylsulfonyl-4-amino-2(1H)- quinazolinones and -2,4(1H,3H)-quinazolinediones were prepared. They were evaluated in vitro for their cytotoxicity against the NCI-60 cancer cell lines. Copyright

Chemical compounds and their use to elevate pyruvate dehydrogenase activity

The use of a compound of the formula (I): wherein: ring C is phenyl or carbon-linked heteroaryl selected from pyridyl, pyrazinyl, pyrimidinyl and pyridazinyl; and wherein said phenyl or heteroaryl is substituted as defined herein; A—B is selected from NHCO, OCH2, SCH2, NHCH2, trans-vinylene, and ethynylene; R1is linked to ring C at a carbon ortho to the position of A—B attachment and is defined herein; n is 1 or 2; R2and R3are alkyl, haloalkyl or together from cycloalkyl or halocycloalkyl as defined herein; in the manufacture of a medicament for use in the elevation of PDH activity in warm-blooded animals such as humans is described. Salts and esters of compounds of formula (I) are also described.

Certain N(4-benzoyl-2-phenyl)-3- trifluoro-2-hydroxy-propanamide derivatives

Compounds of formula I: STR1 wherein, ring C, A-B, R1, n, R2, and R3 have any of the meanings given in the specification, and their pharmaceutically acceptable salts are useful in the treatment of urinary incontinence. Als

Aromatic Nitro-group Displacement Reactions. Part 3. Minor Products of the o-Cyanophenol Synthesis

In dipolar aprotic solvents, the action of cyanide ions on a moderately activated aromatic or heteroaromatic nitro-compound yields, in addition to the o-cyanophenol, a range of products generated through nitro-group reduction.