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159459-52-6

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159459-52-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 159459-52-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,4,5 and 9 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 159459-52:
(8*1)+(7*5)+(6*9)+(5*4)+(4*5)+(3*9)+(2*5)+(1*2)=176
176 % 10 = 6
So 159459-52-6 is a valid CAS Registry Number.

159459-52-6Relevant articles and documents

(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl] -3-(2-fluoro-phenyl)-acrylamide is a potent and efficacious KCNQ2 opener which inhibits induced hyperexcitability of rat hippocampal neurons

Wu, Yong-Jin,Boissard, Christopher G.,Chen, Jie,Fitzpatrick, William,Gao, Qi,Gribkoff, Valentin K.,Harden, David G.,He, Huan,Knox, Ronald J.,Natale, Joanne,Pieschl, Rick L.,Starrett Jr., John E.,Sun, Li-Qiang,Thompson, Mark,Weaver, David,Wu, Dedong,Dworetzky, Steven I.

, p. 1991 - 1995 (2007/10/03)

(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl] -3-(2-fluoro-phenyl)-acrylamide ((S)-2) was identified as a potent and efficacious KCNQ2 opener. This compound demonstrated significant activity in reducing neuronal hyperexcitabil

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