15954-46-8

Basic information

• Product Name: 1-(4-(1-methylcyclohexyl)phenyl)ethan-1-one
• Synonyms: 1-(4-(1-methylcyclohexyl)phenyl)ethan-1-one
• CAS NO: 15954-46-8
• Molecular Weight: 216.323
• Mol File: 15954-46-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(4-(1-methylcyclohexyl)phenyl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(1-methylcyclohexyl)phenyl)ethan-1-one(15954-46-8)
• EPA Substance Registry System: 1-(4-(1-methylcyclohexyl)phenyl)ethan-1-one(15954-46-8)

Safety Data

• Hazardous Substances Data: 15954-46-8(Hazardous Substances Data)

Upstream product

• 89854-70-6 1-methylcyclohexanamine hydrochloride 
• 99-90-1 para-bromoacetophenone 
• 591-49-1 1-methylcyclohex-1-ene 
• 13329-40-3 4-Iodoacetophenone 
• 33026-37-8 (rac)-3-phenyl-3-methylcyclohexanone 
• 71-43-2 benzene 
• 17206-54-1 2-methyl-2-phenyl-cyclohexanone 
• 591-47-9 4-methylcyclohexene 
• 583-59-5 2-Methylcyclohexanol 
• 589-91-3 p-methylcyclohexanol 
• 828-45-5 1-methylcyclohexylbenzene 
• 75-36-5 acetyl chloride 

Downstream Products

• 2948-44-9 1-methoxy-4-(1-methylcyclohexyl)benzene 
• 14962-20-0 4-(1-methylcyclohexyl)phenol 
• 107317-81-7 1-p-acetoxyphenyl-1-methylcyclohexane 
• 14962-16-4 1-p-ethylphenyl-1-methylcyclohexane 
• 63007-39-6 [4-(1-Methyl-cyclohexyl)-phenyl]-acetic acid 

Relevant articles and documents

Dual Nickel/Photoredox-Catalyzed Deaminative Cross-Coupling of Sterically Hindered Primary Amines

We report a method to activate α-3° amines for deaminative arylation via condensation with an electron-rich aldehyde and merge this reactivity with nickel metallaphotoredox to generate benzylic quaternary centers, a common motif in pharmaceuticals and natural products. The reaction is accelerated by added ammonium salts. Evidence is provided in support of two roles for the additive: inhibition of nickel black formation and acceleration of the overall reaction rate. We demonstrate a robust scope of amine and haloarene coupling partners and show an expedited synthesis of ALK2 inhibitors.

Conformational Dependence of 13C SCS in 1-Methyl-1-phenylcyclohexanes

13C chemical shift data are reported for a series of para-substituted 1-methyl-1-phenylcyclohexanes at 22 and -100 deg C.The magnitudes of the SCS at alkyl and cycloalkyl carbon positions are discussed.The SCS at C-methyl and C-4 are significantly differe