15979-82-5Relevant articles and documents
Diarylamine Synthesis via Desulfinylative Smiles Rearrangement
Sephton, Thomas,Large, Jonathan M.,Butterworth, Sam,Greaney, Michael F.
, p. 1132 - 1135 (2022/02/09)
Diarylamines are obtained directly from sulfinamides through a novel rearrangement sequence. The transformation is transition metal-free and proceeds under mild conditions, providing facile access to highly sterically hindered diarylamines that are otherw
Smiles rearrangement for the synthesis of diarylamines
Tian, Xiao,Wu, Ren-Min,Liu, Gang,Li, Zhu-Bo,Wei, He-Lin,Yang, Hao,Shin, Dong-Soo,Wang, Li-Ying,Zuo, Hua
experimental part, p. 118 - 126 (2011/10/02)
A protocol for the one-pot synthesis of diarylamines via Smiles rearrangement under microwave irradiation has been developed. Various diarylamines were effectively synthesized starting from readily available substituted phenols, arylamines and chloroacetyl chloride in moderate to good yields (58-92%). ARKAT-USA, Inc.
Thienopyrimidine and thienopyridine derivatives useful as anticancer agents
-
, (2008/06/13)
The invention relates to compounds of the formulas 1 and 2 and to pharmaceutically acceptable salts and hydrates thereof, wherein X1, R1, R2and R11are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formulas 1 and 2 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formulas 1 and 2.