160204-91-1

Upstream product

• 106-44-5 p-cresol 
• 22002-45-5 2-bromo-4-methylanisole 
• 50597-88-1 2-iodo-4-methylanisole 
• 6627-55-0 2-bromo-p-cresol 

Downstream Products

• 24724-87-6 aristelegin-C 
• 7290-25-7 4-(Bromomethyl)phenyl 5-(bromomethyl)-2-methoxyphenyl ether 
• 83118-65-4 Isodityrosine 
• 854166-24-8 4-methoxy-3,4'-oxy-di-benzoyl chloride 

Relevant academic research and scientific papers

Enantioselective synthesis of dityrosine and isodityrosine via asymmetric phase-transfer catalysis

Application of N-anthracenylmethyl cinchonidinium chloride quaternary ammonium phase-transfer catalysts to the enantio- and diastereoselective synthesis of dityrosine and isodityrosine is reported. Under liquid-liquid phase-transfer conditions the key α-amino acid substituents are introduced with high enantioselectivity (≥95%e.e.).

SYNTHESIS OF L,L-ISODITYROSINE

A study of the development of reaction conditions for implementation of an activated Ullmann diaryl ether condensation reaction may be conducted without amino acid racemization and that has proven suitable for incorporation of a selectively-protected catechol is described and its application to the synthesis of L,L-isodityrosine (1) is detailed.