Enantioselective synthesis of dityrosine and isodityrosine via asymmetric phase-transfer catalysis

Article abstract of DOI:10.1016/S0040-4039(98)02616-1

Application of N-anthracenylmethyl cinchonidinium chloride quaternary ammonium phase-transfer catalysts to the enantio- and diastereoselective synthesis of dityrosine and isodityrosine is reported. Under liquid-liquid phase-transfer conditions the key α-amino acid substituents are introduced with high enantioselectivity (≥95%e.e.).