160237-37-6

Upstream product

• 148930-54-5 (2aR,4S,4aS,6R,9S,11S,12S,12bS)-6,12b-bis(acetyloxy)-9-({(2R,3S)-3-(benzoylamino)-3-phenyl-2-[(triethylsilyl)oxy]propanoyl}oxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9, 10,11,12,12a,12bdodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate 
• 174674-03-4 2'-triethylsilyl-7-methylthiomethylpaclitaxel 
• 160237-25-2 BMS-184476 
• 160334-77-0 (3R,4R)-3-triethylsilyloxy-4-(furan-2-yl)-N-t-butoxycarbonylazetidin-2-one 
• 160237-36-5 7-methylthiomethyl baccatin III 

Relevant academic research and scientific papers

Synthesis and antitumor activity of novel C-7 paclitaxel ethers: Discovery of BMS-184476

The preparation of C-7 paclitaxel ethers is described. Various substituted ethers were prepared via activation of the corresponding methylthiomethyl ether followed by alcohol addition. Variation of the C-7 ether group as well the 3′ side chain position le