16024-55-8

Usage

Uses

Used in Pharmaceutical Industry:
2-(2-Methoxyethoxy)acetyl chloride is used as a reagent for the synthesis of various pharmaceuticals. Its unique chemical structure allows it to participate in a range of organic reactions, contributing to the development of new drugs and medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(2-Methoxyethoxy)acetyl chloride serves as a reagent in the production of agrochemicals. Its role in organic synthesis aids in the creation of compounds that can be used in pesticides, herbicides, and other agricultural products to enhance crop protection and yield.
Used in Dye Industry:
2-(2-Methoxyethoxy)acetyl chloride is utilized as a reagent in the synthesis of dyes. Its involvement in organic reactions facilitates the production of a variety of dyes used in different industries, including textiles, plastics, and printing inks.
Used as a Solvent in Chemical Reactions:
Beyond its role as a reagent, 2-(2-Methoxyethoxy)acetyl chloride also functions as a solvent in various chemical processes. Its properties enable it to dissolve a range of substances, making it a valuable component in numerous chemical reactions and processes.
Used as a Precursor in Organic Synthesis:
2-(2-Methoxyethoxy)acetyl chloride is employed as a precursor in the synthesis of other organic compounds. Its versatility in organic chemistry allows it to be a starting material for the creation of a multitude of organic molecules, expanding the scope of chemical research and development.

InChI:InChI=1/C5H9ClO3/c1-8-2-3-9-4-5(6)7/h2-4H2,1H3

Upstream product

• 16024-56-9 2-(2-methoxyethoxy)acetic acid 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 99135-93-0 (3R,4R)-3,4-Bis(diphenylphosphino)-1-<(2-methoxyethoxy)acetyl>pyrrolidin 
• 195259-52-0 6-Benzyloxy-2-[2-(2-methoxy-ethoxy)-acetyl]-3,4-dihydro-2H-isoquinolin-1-one 
• 186963-32-6 1,4-bis[[(2-methoxyethoxy)methylene]carboxy]benzene 
• 177785-28-3 (S)-4-benzyl-3-<2-(2-methoxyethoxy)ethanoyl>oxazolidin-2-one 
• 650628-84-5 N-(4-formylphenyl)-2-(2-methoxyethoxy)acetamide 
• 917387-12-3 C₂₅H₂₈ClN₅O₆ 
• 1229607-05-9 2-(2-methoxyethoxy)-1-(4-(3-(4-(4-(3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)ureido)naphthalen-1-yloxy)pyridin-2-yl)ureido)piperidin-1-yl)ethanone 
• 1229606-66-9 N-(4-(4-(3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)ureido)naphthalen-1-yloxy)pyridin-2-yl)-2-(2-methoxyethoxy)acetamide 
• 1342826-89-4 N-(4-(7-(4-(3-cyclopropylureido)-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)benzyl)-2-(2-methoxyethoxy)-N-(2-methoxyethyl)acetamide 
• 1012338-82-7 C₁₅H₂₀N₆O₉ 
• 74578-53-3 4-nitrophenyl 2-(2-methoxyethoxy)acetate 
• 72914-00-2 N-(1'-methoxycarbonylethyl)-N-(2'-methoxyethoxyacetyl)-2,3,6-trimethylaniline 
• 118316-49-7 5-(2-methoxyethoxyacetamido)-1-(2,6-dichloro-4-trifluoromethylphenyl)-pyrazole 
• 437603-05-9 2-[(2-methoxyethoxy)methyl]-1-(2-phenoxyethyl)-1H-imidazo[4,5-c]quinolin-4-amine 

Relevant academic research and scientific papers

Polycyclic compounds from aminopolyols and a-dicarbonyls: Structure and application in the synthesis of exoditopic ligands

The structure and stereochemistry of the crystalline 2 : 2 condensation product ("glytham") of glyoxal and tris(hydroxymethyl)aminomethane was conclusively determined by X-ray diffractometric analysis. The singular disposition of the heteroatoms suggests the employment of glytham as starting material for the synthesis of ditopic ligands for metal ions. Some derivatives of glytham were prepared and their binding properties towards alkaline metal ions were preliminarily investigated by ESI-MS and NMR. The Royal Society of Chemistry 2005.

Molecularly imprinted artificial esterases with highly specific active sites and precisely installed catalytic groups

A difficult challenge in synthetic enzymes is the creation of substrate-selective active sites with accurately positioned catalytic groups. Covalent molecular imprinting in cross-linked micelles afforded such active sites in protein-sized, water-soluble nanoparticle catalysts. Our method allowed a systematic tuning of the distance of the catalytic group to the bound substrate. The catalysts displayed enzyme-like kinetics and easily distinguished substrates with subtle structural differences.

IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION

The present invention provides thiazole compounds of Formula I wherein W, Y, R0, R2, R4, R5, R6, R7, X1, X2, X3 and X4 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.

Prodrugs of compounds that inhibit TRPV1 receptor

Compounds of formula (I) wherein A, R1, R2, and R3 are defined in the specification, and which are useful as therapeutic compounds particularly for treating disorders or conditions associated with inflammation, pain, bladd

SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES WITH A CHAIN EXTENSION

The invention relates to substituted cyclohexyl-1,4-diamine derivatives, to a method for their production, to medicaments containing said compounds and to the use of substituted cyclohexyl-1,4-diamine derivatives for producing medicaments.

SUBSTITUTED ACETANILIDES AND BENZAMIDES FOR THE TREATMENT OF ASTHMA AND PULMONARY INFLAMMATION

Substituted acetanilide or benzamide compositions or formulations for delivery by aerosolization are described. The formulation contains an efficacious amount of acetanilide or benzamide compound able to inhibit inflammation in asthmatic lungs. Compounds of the invention are formulated in 5 ml solution of a quarter normal saline having pH between 5.0 and 7.0. The method for treatment of respiratory tract inflammation by a formulation delivered as an aerosol having mass medium average diameter predominantly between 1 to 5 μ, produced by nebulization or dry powder inhaler.

Hepatic enzymatic synthesis and hydrolysis of CoA esters of solvent-derived oxa acids

Many ethylene glycol-derived solvents are oxidized to xenobiotic alkoxyacetic acids (3-oxa acids) by hepatic enzymes. The toxicity of these ubiquitous solvents has been associated with their oxa acid metabolites. For many xenobiotic carboxylic acids, the toxicity is associated with the CoA ester of the acid. In this study, related alkoxyacetic acids were evaluated as potential substrates for acyl-CoA synthetases found in mitochondrial, peroxisomal, and microsomal fractions isolated from rat liver. Likewise, chemically synthesized oxa acyl-CoAs were used as substrates for acyl-CoA hydrolases associated with the same rat liver fractions. Activities of the xenobiotic oxygen-substituted substrates were compared with analogous physiologic aliphatic substrates by UV-vis spectrophotometric methods. All of the solvent-derived oxa acids were reasonable substrates for the acyl-CoA synthetases, although their activity was usually less than the corresponding physiologic acid. Acyl-CoA hydrolase activities were decreased compared with acyl-CoA synthetase activities for all substrates, especially for the oxa acyl-CoAs. These studies suggest that these xenobiotic carboxylic acids may be converted to reactive acyl-CoA moieties which will persist in areas of the cell proximal to lipid synthesis, β-oxidation, protein acylation, and amino acid conjugation. The interaction of these xenobiotic acyl-CoAs with those processes may be important to their toxicity and/or detoxification.

Novel delta dicarbonyl compounds and methods for using same

Amidomethyl esters, carbonylmercaptomethyl esters, keto-containing esters, amidomethyl thioesters, amidomethyl amides, and methylene dithioesters are disclosed. The novel compounds have two carbonyl groups connected by a linking moiety having an oxygen, s

5-amino-4-hydroxyhexanoic acid derivatives

Compounds of formula I STR1 or their hydroxy-protected derivatives, and compounds of formula I' STR2 wherein T is an acyl radical of formula Z STR3 wherein Rz is unsubstituted or substituted hydrocarbyl wherein at least one carbon atom has been replaced by a hetero atom with the proviso that a hetero atom is not bonded directly to the carbonyl to which the radical Rz is bonded, alkyl having two or more carbon atoms, lower alkenyl, lower alkynyl, aryl or unsubstituted or substituted amino, and wherein the radicals R1, B1, R2, R3, A1, A2 and NR4 R5 are as defined in the description, and precursors thereof, are described. The compounds have pharmaceutical activity, for example in the treatment of retroviral diseases, such as AIDS.

Structure-reactivity relationship in interlocked molecular compounds and in their supramolecular model complexes

Examination of the pseudorotaxane-like geometries adopted in the solid state by a series of 1:1 complexes revealed significant differences in the hydrogen bonding interactions between oxygen atoms in some hydroquinone-based guests carrying polyether/polye