74578-53-3Relevant academic research and scientific papers
Molecularly imprinted artificial esterases with highly specific active sites and precisely installed catalytic groups
Hu, Lan,Zhao, Yan
, p. 5580 - 5584 (2018/08/17)
A difficult challenge in synthetic enzymes is the creation of substrate-selective active sites with accurately positioned catalytic groups. Covalent molecular imprinting in cross-linked micelles afforded such active sites in protein-sized, water-soluble nanoparticle catalysts. Our method allowed a systematic tuning of the distance of the catalytic group to the bound substrate. The catalysts displayed enzyme-like kinetics and easily distinguished substrates with subtle structural differences.
Prodrugs of compounds that inhibit TRPV1 receptor
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Page/Page column 29-30, (2010/11/27)
Compounds of formula (I) wherein A, R1, R2, and R3 are defined in the specification, and which are useful as therapeutic compounds particularly for treating disorders or conditions associated with inflammation, pain, bladd
