16024-56-9

Basic information

• Product Name: 2-(2-Methoxyethoxy)acetic acid
• Synonyms: TIMTEC-BB SBB008497;3,6-DIOXAHEPTANOIC ACID;2-(2-METHOXYETHOXY)ACETIC ACID;(2-methoxyethoxy)acetic acid;2-(2-METHOXYETHOXY)ACETIC ACID, TECH.;2-(2-Methoxyethoxy)Acetic;o-(2-methoxyethyl)glycolic acid;(2-Methoxyethoxy)essigsure
• CAS NO: 16024-56-9
• Molecular Formula: C₅H₁₀O₄
• Molecular Weight: 134.13
• EINECS: 240-161-6
• Product Categories: Heterocyclic Compounds
• Mol File: 16024-56-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 245-250 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.18 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00651mmHg at 25°C
• Refractive Index: n20/D 1.436(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.40±0.10(Predicted)
• Water Solubility: Fully miscible in water.
• BRN: 1753567
• CAS DataBase Reference: 2-(2-Methoxyethoxy)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Methoxyethoxy)acetic acid(16024-56-9)
• EPA Substance Registry System: 2-(2-Methoxyethoxy)acetic acid(16024-56-9)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 1
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 16024-56-9(Hazardous Substances Data)

Usage

Chemical Properties

Colorless to pale yellow liquid

InChI:InChI=1/C5H10O4/c1-8-2-3-9-4-5(6)7/h2-4H2,1H3,(H,6,7)/p-1

Upstream product

• 111-77-3 2-(2-methoxyethoxy)ethyl alcohol 
• 57982-39-5 3,6-dioxaheptanoic acid ethyl ester 
• 109-86-4 2-methoxy-ethanol 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 79-11-8 chloroacetic acid 
• 111-96-6 diethylene glycol dimethyl ether 

Downstream Products

• 157303-82-7 (R)-N-(1-phenyl-2-piperidinoethyl)-2-(2-methoxyethyloxy)acetamide 
• 16024-55-8 2-(2-methoxyethoxy)acetyl chloride 
• 130611-26-6 4-(2-methoxy-ethoxy)-3-oxo-butyric acid ethyl ester 
• 635302-13-5 N-[O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-(1->3)-O-(2,4,6-tri-O-acetyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-acetyl-1-β-D-glucopyranosyl]-2-(2-methoxyethoxy)acetamide 
• 847749-06-8 (Pd(C₆H₃(O(CH₂)9CH₃)CHNC₆H₄O(CH₂)9CH₃)OCOCH₂OCH₂CH₂OCH₃)2 
• 847739-56-4 (Pd(C₆H₃(O(CH₂)5CH₃)CHNC₆H₄O(CH₂)5CH₃)OCOCH₂OCH₂CH₂OCH₃)2 
• 17640-28-7 dioxa-3,6 heptanoate de methyle 
• 74578-53-3 4-nitrophenyl 2-(2-methoxyethoxy)acetate 

Relevant articles and documents

Electroorganic synthesis in oil-in-water (O/W) nanoemulsion: TEMPO-mediated electrooxidation of amphiphilic alcohols in water

Oil-in-water nanoemulsion which consisted of TEMPO, amphiphilic alcohols, and water offered unique reaction environments for electrooxidation of the alcohols to give the corresponding carboxylic acids in good to excellent yields.

BENZODICYCLOALKANE DERIVATIVE, PREPARATION METHOD AND USE THEREOF

It is provided herein a benzobicycloalkane derivative, and a preparation method and use thereof. In particular, it is provided herein a compound of Formula (I), or a pharmaceutically acceptable salt, stereoisomer or solvate thereof, a preparation method, and a use thereof in preparation of drugs for treating pain.

Ceria supported gold-platinum catalysts for the selective oxidation of alkyl ethoxylates

This work covers the development of a ceria based AuPt catalyst for the selective aerobic oxidation of alkyl ethoxylates to their corresponding carboxylic acids. By optimizing metal loading and the Au to Pt ratio the activity of the catalyst could be increased significantly, while maintaining total selectivity. Although the choice of ceria as a support helped to suppress intermediate metal leaching, the catalyst still showed poor long-term stability in repeated batches. The cause for deactivation could finally be identified by TPR studies as over-oxidation. These suspicions were confirmed by a long-term stability study in continuous-mode. It proved to be possible to deactivate the catalyst on purpose by employing unfavourable oxidising reaction conditions, i.e. low substrate concentrations and excess oxygen. By avoiding such unfavourable conditions either in continuous-flow mode or in repeated batches, the long-term stability of the catalyst increased tremendously. A substrate screening of various ethoxylates showed that the catalyst was very well-suited to selectively oxidize a wide range of alkyl ethoxylates.