160247-32-5Relevant academic research and scientific papers
Asymmetric synthesis. XXXIII. Diastereoselective alkylation of N,N-substituted amides
Micouin, Laurent
, p. 7223 - 7226 (1994)
A series of α-substituted amides 3 and 7-9 has been synthesized in enantiomerically pure form by diastereoselective alkylation of N-alkyl phenylglycinol amides 2 and 4-6 respectively. A rigid amide enolate has been postulated to explain the observed diast
