Tetrahedron Letters p. 7223 - 7226 (1994)
Update date:2022-08-03
Topics:
Micouin, Laurent
A series of α-substituted amides 3 and 7-9 has been synthesized in enantiomerically pure form by diastereoselective alkylation of N-alkyl phenylglycinol amides 2 and 4-6 respectively. A rigid amide enolate has been postulated to explain the observed diast
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