160327-08-2Relevant academic research and scientific papers
Synthesis, characterization and biological activity of (Z)-1-[2]-1-cyclopentanol and their arylhalostannyl derivatives
Dai, Hui Cong,Ying, Qihua,Wang, Xiao Hong,Yue, Su Mei,Pan, Hua De,Chen, Xi
, p. 2503 - 2509 (2008/10/09)
The synthesis and characterization by elemental analysis, IR and 1H NMR of (Z)-1 - 1-cyclopentanol,CH2(CH2)3C(OH)CHCHSnPh 3 (1) and (Z)-1 - 1-cyclopentanol, CH2(CH2)3C(OH)CHCHSn(p-toly)3 (2) are described, together with their halodemetallation by I2, Br2 and ICl to yield derivatives of the types CH2(CH2)3C(OH)CHCHSnAr3-nX n (Ar = phenyl or p-tolyl ; n = 1, 2 ; X = I, Br, Cl). The solid-state structures of two compounds have been determined by X-ray diffraction analysis. In the crystal of CH2(CH2)3C(OH)CHCHSnph3 (1) the Sn atom has a distorted tetrahedral geometry but intramolecular contact with the hydroxyl O atom has not been found. A trigonal bipyramidal geometry is found in CH2(CH2)3CC(OH)CHCH SnphBr2(11), in which OSn - interaction is noted [2.446(8) A] The biological activity of the title complexes is also investigated.
SYNTHESIS AND CHARACTERIZATION OF THE CIS AND TRANS ISOMERS OF Ph3Sn-CH=CH-C(OH)RR' COMPOUNDS AND THEIR GEM ANALOGS. EVIDENCE FOR AN INTRAMOLECULAR HO->Sn INTERACTION IN THE SOLID AND SOLUTION STATE
Kayser, Francois,Biesemans, Monique,Delmotte, Ann,Hendrix, Robert,Malschaert, Patrick,et al.
, p. 273 - 284 (2007/10/02)
The cis and trans isomers of compounds of the type Ph3Sn-CH=CH-C(OH)RR' as well as their gem analogs were synthesized and characterized.Moessbauer spectroscopy enabled to assess the presence of weak intramolecular HO->Sn interactions in the cis and gem isomers in the solid state.In solution, the existence of such coordinations was evidenced by 13C and 119Sn Secondary Isotope Multiplet of Partially Labelled Entities (SIMPLE) NMR.We correlate the results of our NMR experiments with the reactivity of these compounds towards iodine.
