160343-91-9

Upstream product

• 5336-08-3 D-Ribono-1,4-lactone 
• 160343-78-2 (3aR,6aR)-6-{{[(1,1-dimethylethyl)dimethylsilyl]oxy}methyl}-3a,6a-dihydro-2,2-dimethyl-4H-cyclopenta[d]-1,3-dioxol-4-one 
• 160343-79-3 (3aS,4S,6aR)-6-{{[(1,1-dimethylethyl)dimethylsilyl]oxy}methyl}-3a,6a-dihydro-2,2-dimethyl-4H-cyclopenta[d]-1,3-dioxol-4-ol 
• 100-39-0 benzyl bromide 
• 30725-00-9 2,3-O-isopropylidene-D-ribonic-γ-lactone 
• 117307-62-7 (3aR,6aR)-6-Benzyloxymethyl-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-one 
• 89291-76-9 (1S,4R,5S)-(-)-3-<(benzyloxy)methyl>-4,5-O-isopropylidene-2-cyclopenten-1-ol 
• 160343-90-8 <1R-(1α,2α,3α,4α,5α)>-1-<(Benzyloxy)methyl>-2,3-(isopropylidenedioxy)-4-<(4-methoxybenzyl)oxy>-6-oxabicyclo<3.1.0>hexane 
• 160531-14-6 3,4-O-Isopropylidene-aldehydo-L-ribo-penturono-5,2-lactone 
• 160343-89-5 <1S-(1α,4α,5α)>-3-<(Benzyloxy)methyl>-4,5-(isopropylidenedioxy)-1-<(4-methoxybenzyl)oxy>-2-cyclopentene 
• 160343-87-3 <1S-(1α,4α,5α)>-3-<<(tert-Butyldimethylsilyl)oxy>methyl>-4,5-(isopropylidenedioxy)-1-<(4-methoxybenzyl)oxy>-2-cyclopentene 
• 160343-88-4 <1S-(1α,4α,5α)>-3-(Hydroxymethyl)-4,5-(isopropylidenedioxy)-1-<(4-methoxybenzyl)oxy>-2-cyclopentene 
• 160343-77-1 (Z)-5-O-(tert-Butyldimethylsilyl)-4,5-didehydro-2,3-O-isopropylidene-D-erythro-penturono-1,4-lactone 

Downstream Products

• 160343-93-1 <1R-(1α,2β,3β,4β,5β)>-5-Amino-1-<(benzyloxy)methyl>-2,3-(isopropylidenedioxy)-1,4-cyclopentanediol 
• 160343-94-2 <1R-(1α,2β,3β,4β,5β)>-<1-<(Benzyloxy)methyl>-1,2,3,4-tetrahydroxycyclopentane-5-yl>amino (2,3,4,5-tetra-O-benzyl-1-deoxy-α-D-glucopyranos-1-yl)amino thioketone 
• 160343-95-3 <3aR-(3aα,4α,5β,6β,6aα)>-4-<(Benzyloxy)methyl>-2-<(2,3,4,6-tetra-O-benzyl-1-deoxy-α-D-glucopyranos-1-yl)-amino>-3a,5,6,6a-tetrahydro-4H-cyclopentoxazole-4,5,6-triol 
• 160344-09-2 <3aR-(3aα,4α,5β,6β,6aα)>-4-<(Benzyloxy)methyl>-2-(benzylamino)-3a,5,6,6aα-tetrahydro-4H-cyclopentoxazole-4,5,6-triol 
• 160344-08-1 <1R-(1α,2β,3β,4β,5β)>-<1-<(Benzyloxy)methyl>-1,2,3,4-tetrahydroxycyclopent-5-yl>amino benzylamino thioketone 
• 160343-92-0 <1R-(1α,2β,3β,4β,5β)>-5-Azido-1-<(benzyloxy)methyl>-2,3-(isopropylidenedioxy)-1,4-cyclopentanediol 

Relevant academic research and scientific papers

Chiral pool synthesis of 4a-substituted carbocyclic cyclopentanoid nucleoside precursors, I

A suitable protected D-ribono-1,4-lactone derivative has been used for the straightforward chiral pool synthesis of cyclopentanoid nucleoside precursors. Thus, epoxidation followed by deoxygenation or regioselective ring opening led to nucleoside precurso

Stereocontrolled syntheses of 6-epi-trehazolin and 6-epi-trehalamine from D-ribonolactone

6-epi-Trehazolin was synthesized in a stereocontrolled manner, and this synthesis proved that an oxazine structural isomer of 6-epi-trehazolin does not exist.

Synthesis of 6-epi-trehazolin from D-ribonolactone: Evidence for the non-existence of a 5,6-ringfused structural isomer of 6-epi-trehazolin

6-Epi-trehazolin was synthesized in a stereocontrolled manner, and this synthesis provided proof for the non-existence of oxazine structural isomer of 6-epi-trehazolin.