160348-97-0Relevant academic research and scientific papers
Protecting group for carboxyl function: Mild and facile cleavage of 2- cyanoethyl ester under non-hydrolytic conditions
Kita,Maeda,Takahashi,Fukui,Ogawa,Hatayama
, p. 147 - 150 (1994)
The use of the 2-cyanoethyl group for carboxyl-protection is described. This group was readily introduced by esterification using ethylene cyanohydrin and the deprotection was carried out under mild conditions using tetrabutylammonium fluoride in dimethylformamide-tetrahydrofuran.
Enantioselective Folding at the Cyclodextrin Surface
Eliseev, Alexey V.,Iacobucci, Guillermo A.,Khanjin, Nikolai A.,Menger, F. M.
, p. 2051 - 2052 (2007/10/02)
Spectroscopic and kinetic studies of β-cyclodextrin-linked L- and D-phenylalanine cyanoethyl esters in aqueous solution reveal an unusual intramolecular complexation mode where the hydrophobic portion of the amino acid resides outside the host cavity; L- and D-derivatives show different binding geometries and energies.
