160588-45-4 Usage
Uses
Used in Molecular Imaging:
10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE is used as a fluorescent probe for detecting DNA and RNA, enabling researchers to visualize and study the structure, function, and interactions of these biomolecules in various biological processes.
Used in Biological Research:
10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE serves as a valuable tool in biological research, particularly in fluorescence-based assays, where it aids in the investigation of cellular processes, protein-protein interactions, and other molecular events.
Used in Diagnostic Imaging:
10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE has been studied for its potential use in diagnostic imaging, where its fluorescent properties can enhance the visualization of biological structures and processes, contributing to the early detection and monitoring of diseases.
Used in Organic Electronics:
10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE's optical properties have been explored for applications in organic electronics, where it can be employed in the development of fluorescent sensors and other optoelectronic devices, leveraging its high photostability and fluorescence characteristics.
Used in Pharmaceutical Industry:
10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE is used as a fluorescent marker in drug discovery and development, facilitating the tracking and analysis of drug candidates within biological systems, thus aiding in the optimization of drug efficacy and safety.
Used in Environmental Science:
In environmental science, 10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE can be employed as a tracer to monitor the behavior and fate of pollutants, providing insights into environmental processes and contributing to the development of effective remediation strategies.
Used in Forensic Science:
10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE can be utilized as a forensic tool, where its fluorescent properties can aid in the detection and analysis of trace evidence, supporting investigations in forensic cases.
Used in Material Science:
10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE's optical properties make it a candidate for use in the development of advanced materials with specific fluorescence characteristics, such as in the creation of sensors, imaging devices, and other optoelectronic applications.
Used in Nanotechnology:
10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE can be integrated into nanoscale systems, where it can serve as a fluorescent component in the design of nanomaterials with targeted functionalities, such as in drug delivery or imaging agents.
Used in Biochemistry:
In biochemistry, 10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE is used as a fluorescent label for biomolecules, enabling researchers to study their behavior, interactions, and dynamics within complex biological systems, thus advancing our understanding of biochemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 160588-45-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,5,8 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 160588-45:
(8*1)+(7*6)+(6*0)+(5*5)+(4*8)+(3*8)+(2*4)+(1*5)=144
144 % 10 = 4
So 160588-45-4 is a valid CAS Registry Number.
InChI:InChI=1/C26H18F2N2O/c27-23-13-17(9-11-29-23)15-26(16-18-10-12-30-24(28)14-18)21-7-3-1-5-19(21)25(31)20-6-2-4-8-22(20)26/h1-14H,15-16H2
160588-45-4Relevant articles and documents
Crystalline 10,10-Bis((2-fluoro-4-pyridinyl)methyl)-9(10H)-Anthracenone and an improved process for preparing the same
-
, (2008/06/13)
The present invention relates to processes for the synthesis of a crystalline polymorph of 10,10-Bis((2-fluoro-4-pyridinyl)methyl)-9(10H)-Anthracenone in high purity. The product is useful in the synthesis of pharmaceutical compounds for the reduction of cholinergic system dysfunction.
Efficient pyridinylmethyl functionalization: Synthesis of 10,10-bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone (DMP 543), an acetylcholine release enhancing agent
Pesti,Huhn,Yin,Xing,Fortunak,Earl
, p. 7718 - 7722 (2007/10/03)
2-Fluoro-4-methylpyridine (3) is efficiently functionalized by chlorination, hydrolysis and methane-sulfonylation into the novel alkylating agent 7. This mesylate is used for the bisalkylation of anthrone under carefully defined conditions to prepare the cognition enhancer drug candidate 1. This process proceeds in up to 37% overall yield and is adaptable for large scale synthesis.
2-Fluoro-4-pyridinylmethyl analogues of linopirdine as orally active acetylcholine release-enhancing agents with good efficacy and duration of action
Earl, Richard A.,Zaczek, Robert,Teleha, Christopher A.,Fisher, Barbara N.,Maciag, Carla M.,Marynowski, Maria E.,Logue, Andrew R.,Tam, S. William,Tinker, William J.,Huang, Shiew-Mei,Chorvat, Robert J.
, p. 4615 - 4622 (2007/10/03)
In an effort to improve the pharmacokinetic and pharmacodynamic properties of the cognition-enhancer linopirdine (DuP 996), a number of core structure analogues were prepared in which the 4-pyridyl pendant group was systematically replaced with 2-fluoro-4
BLOCKADE OF NEURONAL M-CHANNELS AS A THERAPEUTIC APPROACH TO THE TREATMENT OF NEUROLOGICAL DISEASE
-
, (2008/06/13)
Compounds which block neuronal M-channels are useful for treating conditions involving neurotransmitter deficiencies, traumatic brain injury, or the depressive phase of bipolar disorder. Compounds can be evaluated for utility in treating these conditions by determining whether they are capable of blocking neuronal M-channels.
