160691-37-2

Upstream product

• 2973-86-6 lithium thiophenoxide 
• 86534-97-6 (2S,3S,4S,5R,6S)-7-hydroxy-3,5-(isopropylidenedioxy)-2,4,6-trimethylheptyl p-toluenesulfonate 
• 86534-96-5 Toluene-4-sulfonic acid (S)-2-[(4S,5S,6R)-6-((S)-2-benzyloxymethoxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-propyl ester 
• 86534-95-4 (2S,3S,4R,5R,6S)-7-Benzyloxymethoxy-2,4,6-trimethyl-heptane-1,3,5-triol 
• 86534-93-2 (2R,3R,4R,5R,6S)-7-Benzyloxymethoxy-5-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,4,6-trimethyl-heptanoic acid 2,6-dimethyl-phenyl ester 
• 86534-88-5 (2S,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-hydroxy-2,4-dimethyl-pentanoic acid methyl ester 
• 86534-89-6 (2S,3R,4S)-5-Benzyloxymethoxy-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-pentanoic acid methyl ester 
• 86534-91-0 (2S,3R,4S)-5-Benzyloxymethoxy-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-pentanal 
• 86534-90-9 (2R,3S,4S)-5-Benzyloxymethoxy-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-pentan-1-ol 
• 82281-55-8 (3S,4R,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-3,5-dimethyl-1-trimethylsilanyloxy-cyclopentene 
• 160691-36-1 (2S,3S,4S,5R,6S)-7-(benzyloxy)-3,5-(isopropylidenedioxy)-2,4,6-trimethylheptyl p-toluenesulfonate 
• 160691-35-0 (2S,3S,4S,5R,6S)-7-(benzyloxy)-3,5-dihydroxy-2,4,6-trimethylheptyl p-toluenesulfonate 
• 140925-44-6 (2S,3S,4R,5R,6S)-7-(benzyloxy)-2,4,6-trimethyl-1,3,5-heptanetriol 
• 116661-41-7 (2S,4R,5R)-1-(benzyloxy)-5-hydroxy-2,4,6-trimethylhept-6-en-3-one 

Downstream Products

• 86534-98-7 (SRS,2S,3R,4S,5R,6R)-3,5-(isopropylidenedioxy)-2,4,6-trimethyl-7-(phenylsulfinyl)heptan-1-ol 
• 160691-42-9 C₄₁H₆₉Cl₃O₉Si₂ 

Relevant academic research and scientific papers

Studies in macrolide synthesis: A stereocontrolled synthesis of oleandolide employing reagent- and substrate-controlled aldol reactions of (S)-1-(benzyloxy)-2-methylpentan-3-one

A highly stereocontrolled total synthesis of oleandolide (2), the aglycon of the macrolide antibiotic oleandomycin (1), has been completed in 8% overall yield (20 steps longest linear sequence, 26 steps in total) with 90% overall diastereoselectivity. Ini

STUDIES IN MACROLIDE SYNTHESIS: A SYNTHESIS OF TWO CHIRAL FRAGMENTS OF OLEANDOMYCIN AND LANKAMYCIN

A synthesis of the two structurally-related chiral fragments, C1-C7 and C8-C13, of oleandomycin and lankamycin is described.