1608-68-0Relevant academic research and scientific papers
An efficient method to prepare aryl acetates by the carbonylation of aryl methyl ethers or phenols
Zhang, Dejin,Yang, Guoqiang,Xiong, Junping,Liu, Jia,Hu, Xingbang,Zhang, Zhibing
, p. 2683 - 2687 (2021/02/16)
Synthesis of valuable chemicals from lignin based compounds is critical for the application of biomass. Here, we develop a method of preparing aryl acetates by the carbonylation of aryl methyl ethers or phenols under low CO pressure. Good to excellent yields of aryl acetates were obtained using different substrates, and a possible reaction mechanism was proposed by conducting a series of control experiments. This method may provide a potential way for the utilization of lignin.
2, 4-diaminopyrimidine compound containing phenol fragment, preparation method, pharmaceutical compositions and use thereof
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Paragraph 0130-0133, (2018/04/02)
The invention discloses a 2, 4-diaminopyrimidine compound containing phenol fragment with a general formula I shown in the specification, pharmaceutically acceptable salts or pharmaceutically acceptable solvates, a preparation method thereof, pharmaceutical compositions containing the compounds, and use of the compounds in preparation of drugs for preventing or treating anaplastic lymphoma kinaserelated abnormal cell proliferation, morphological changes, hyperkinesia and other associated diseases in organisms, and angiogenesis or cancerometastasis associated diseases, especially use in drugsfor treating or preventing tumor growth and metastasis.
ANALOGS OF PROPOFOL, PREPARATION THEREOF AND USE AS ANESTHETICS
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, (2009/12/23)
Compounds of formula (I) wherein X is H or F and pharmaceutically acceptable salts thereof are useful as anesthetics.
Method of treating bone disease with pyridine, carboxamide and carboxylic derivatives
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, (2008/06/13)
Treatment of osteopathic comprising administering as an active ingredient a compound represented by the following formula (I), (II) or (III): STR1
Antioxidant building blocks I. The unexpected C-acetylation of 2,6-Di-tert-butylphenol with isopropenyl acetate
Gizur, Tibor,Ferenczy, Gyoergy G.,Agai-Csongor, Eva,Domany, Gyoergy
, p. 1244 - 1247 (2007/10/03)
While the reaction of some 2-substituted and 2,6-disubstituted phenols with isopropenyl acetate resulted in the corresponding phenol acetates, in the reaction of 2,6-di-tert-butylphenol, a useful starting material of antioxidant building blocks, under the same conditions 4-acetyl-2,6-di-tert-butylphenol was the only product.
OXYGENATION OF AROMATIC AND ALIPHATIC HYDROCARBONS BY A NEW REAGENT SYSTEM, Fe(CH3CN)6(2+)-H2O2-Ac2O: AN EFFECTIVE MODEL REAGENT FOR MONO-OXYGENASE
Kotani, Eiichi,Kobayashi. Shigeki,Ishii, Yoko,Tobinaga, Seisho
, p. 4671 - 4679 (2007/10/02)
Reactions of aromatic and aliphatic hydrocarbons with a new system, Fe(CH3CN)6(2+) - H2O2 - Ac2O in CH3CN, gave oxygenation products with fairly high reaction efficiency ( Tables I and II )compared to known to reagent systems used as enzyme models for mono-oxygenases.Investigations of the mechanism of these reactions indicated the involvement of either complex C.FeIV(OH)(OAc)(2+), or complex D, FeIV(OAc)(2+), dependig on the organic substrate.Keywords-oxygenation; aromatic hydrocarbon; aliphatic hydrocarbon; hexakisacetonitrile iron(II) perchlorate; hydrogen peroxide; enzyme model; mono-oxygenase
Formation and reactivity of 1,3-benzodioxol-2-yl, 1,3-benzodioxan-2-yl, and related radicals. A search for an aromatic analog of the radical acetoxy rearrangement (Surzur-Tanner reaction)
Shahidi, Fereidoon,Tidwell, Thomas T.
, p. 1092 - 1097 (2007/10/02)
Reaction of the 1,3-dioxole, 9, the 1,3-dioxan, 18, and the 1,3-dioxepin, 29, with tert-butoxy radicals gave evidence in each case for formation of the corresponding 1,1-dioxyethyl radicals.No conclusive evidence for formation of any of these radicals by cyclization of acetoxyaryl radicals could be obtained.Several of the 1,1-dioxyethyl radicals reacted by rearrangement.
Acetylation by Keten of Phenols supported on Solid Adsorbents
Chihara, Teiji,Teratani, Shousuke,Ogawa, Haruo
, p. 1120 (2007/10/02)
Even hindered phenols, when adsorbed on solids such as silica gel and alumina, add to keten without heating or sulphuric acid catalyst.
Aromatic Diazonium Salts, X. - A One-Pot Procedure for the Jacobson Synthesis of Indazole
Ruechardt, Christoph,Hassmann, Volker
, p. 908 - 927 (2007/10/02)
Procedures are described for a one-pot synthesis of 1H-indazole and substituted indazoles 3 in good yield (Table 1) from o-toluidines 2, alkyl nitrite or nitrous oxides, potassium acetate, and acetic anhydride in benzene.The spectroscopic properties of substituted indazoles (Tables 2-4) are discussed. - 4-Phenylcinnoline (18) is prepared by the same procedure from o-(α-methylenebenzyl)aniline.
