16080-63-0Relevant academic research and scientific papers
Oxidative Radical Addition-Cyclization of Sulfonyl Hydrazones with Simple Olefins by Binary Acid Catalysis
Zhong, Xingren,Lv, Jian,Luo, Sanzhong
, p. 3150 - 3153 (2016/07/13)
An unprecedented binary acid accelerated oxidative radical annulation of sulfonyl hydrazones with simple olefins is described. Notably, this method provides a novel oxidative radical cycloaddition for the construction of six-member heterocycles. It offers a rapid and efficient approach to tetrahydropyridazines which are key structural motifs in pharmaceutically active compounds.
B(C6F5)3-catalyzed metal-free hydrogenation of 3,6-diarylpyridazines
Wang, Wei,Meng, Wei,Du, Haifeng
, p. 5945 - 5948 (2016/04/26)
This paper describes the first metal-free hydrogenation of 3,6-diarylpyridazines, which was successfully realized using B(C6F5)3 as a catalyst. A variety of 1,4,5,6-tetrahydropyridazine derivatives were furnished in 85-95%
