160849-59-2

Upstream product

• 174148-49-3 (3aS,4R,7aS)-1-Benzyl-4-triisopropylsilanyloxymethyl-1,3a,4,7a-tetrahydro-pyrano[4,3-d]oxazol-2-one 
• 148302-25-4 1,5-anhydro-2,3-dideoxy-3-(trichloroacetamido)-6-O-(triisopropylsilyl)-D-ribo-hex-1-enopyranose 
• 148302-24-3 3-amino-1,5-anhydro-2,3-dideoxy-3,O,4,N-<(trichloromethyl)oxazolino>-6-O-(triisopropylsilyl)-D-ribo-hex-1-enopyranose 
• 100-39-0 benzyl bromide 
• 124-63-0 methanesulfonyl chloride 
• 160849-58-1 (3aS,4R,7aS)-1-Benzyl-4-hydroxymethyl-1,3a,4,7a-tetrahydro-pyrano[4,3-d]oxazol-2-one 
• 137915-37-8 1,2-dideoxy-6-O-triisopropylsilyl-D-arabino-1-hexenopyranose 

Downstream Products

• 160849-60-5 1,5-anhydro-3-(benzylamino)-3,N,4,O-carbonyl-2,3,6-trideoxy-D-ribo-hexa-1,5-dienopyranose 

Relevant academic research and scientific papers

Epoxides Derived from Pyranosyl Dienes: Unusually Stable Glycosyl Donors

A pyranosyl diene appropriately substituted for use in a total synthesis of staurosporine has been synthesized.The mono-epoxides and bis-epoxides obtained from treatment of this diene with dimethyldioxirane are unusually stable.

Staurosporine and ent-staurosporine: The first total syntheses, prospects for a regioselective approach, and activity profiles

The total syntheses of staurosporine and ent-staurosporine have been achieved. Both glycosidic bonds were built from glycal precursors. The first was constructed by intermolecular coupling of an indole anion with a 1,2-anhydrosugar derived from an endo-glycal by direct epoxidation. The second bond was assembled from an exo-glycal by intramolecular iodoglycosylation.