16089-79-5Relevant articles and documents
Development of a selenide-based fluorescent probe for imaging hypochlorous acid in lysosomes
Qu, Zongjin,Ding, Junxia,Zhao, Meiyu,Li, Peng
, p. 1 - 8 (2015)
The development of fluorescent probes for hypochlorous acid (HOCl) has received intense attention because of the biological significance of HOCl. In this work, a novel fluorescent probe based on a selenide switch for the detection of HOCl in lysosomes has been designed and synthesized on a 1,8-naphthalimide scaffold. The probe exhibited a high selectivity for HOCl over various reactive oxygen species (ROS) with a fast response and a large fluorescence enhancement in aqueous media. Confocal microscopy imaging of living cells indicated that the probe was able to accumulate in lysosomes and was successfully applied to imaging exogenous HOCl in living cells. Attempts of using Lyso-NI-Se to image HOCl in stimulated RAW264.7 cells failed, probably due to the absence of endogenous HOCl in lysosomes or the undesirable detection limit.
Palladium Nanoparticles Supported on Nitrogen-rich Containing Melamine-based Microporous Covalent Triazine Polymers as Efficient Heterogeneous Catalyst for C?Se Coupling Reactions
Sadhasivam, Velu,Balasaravanan, Rajendiran,Chithiraikumar, Chinnadurai,Siva, Ayyanar
, p. 3833 - 3844 (2018/07/30)
In the present work, microporous nitrogen containing covalent triazine polymers (CTPs) TATAM was synthesized from condensation of 4,4′4′′-(1,3,5-triazine-2,4,6-triyl) tribenzaldehyde (TATA) and melamine under solvothermal conditions to obtain nitrogen- rich triazine containing polymeric supported materials (TATAM). Further, palladium nanoparticles (Pd NPs) were supported on TATAM polymeric networks (Pd@TATAM). The synthesized Pd@TATAM CTPs material was thoroughly characterized by FT-IR, UV-DRS, solid state 13C-CPMAS, XPS, powder X-ray diffraction, TGA, SEM, TEM. In addition, the characterized Pd@TATAM CTPs were applied to check the catalytic application. The Pd@TATAM was shown to be an efficient and reusable heterogeneous solid catalyst for the formation of C?Se bond through coupling of aryl halide and elemental selenium, dimethyl sulfoxide as a solvent at 100 °C for about 6 h. Besides the absence of metal leaching for catalytic system, it is also observed that the catalyst can be reused for three consecutive cycles with a minimal decrease in its activity.
DMSO/iodine-catalyzed oxidative C-Se/C-S bond formation: A regioselective synthesis of unsymmetrical chalcogenides with nitrogen- or oxygen-containing arenes
Saba, Sumbal,Rafique, Jamal,Braga, Antonio L.
, p. 3087 - 3098 (2016/05/24)
A convenient metal-free and solvent-free iodine-catalyzed regioselective greener protocol to access different types of unsymmetrical chalcogenides with nitrogen- or oxygen-containing arenes through oxidative C-Se/C-S formation via direct C(sp2)-H bond activation was developed. The products were obtained in good to excellent yields using [O or N]-containing arenes, half equiv. of various odorless diorganyl dichalcogenides (S/Se), iodine (20 mol%) as the catalyst and 3 equiv. of DMSO as the oxidant, applying MW irradiation for 10 min.
