1609281-86-8

Usage

Uses

AZD 3264 is a scalable IKK2 Inhibitor .

Upstream product

• 1996-29-8 1-bromo-4-chloro-2-fluorobenzene 
• 1435-52-5 2,5-dibromofluorobenzene 
• 136434-77-0 4-bromo-3-fluoroiodobenzene 
• 1609116-53-1 C₁₅H₁₉BrClNO₃ 
• 1609116-54-2 C₁₅H₂₁BClNO₅ 
• 1609116-56-4 tert-butyl(3S)-3-[2-(4-carbamoyl-5-ureido-2-thienyl)-5-(3,5-dimethylisoxazol-4-yl)phenoxy]pyrrolidine-1-carboxylate 
• 1609116-57-5 C₁₅H₁₉Br₂NO₃ 
• 1609116-58-6 C₁₅H₁₉BrINO₃ 
• 1609116-50-8 tert-butyl (3S)-3-[2-bromo-5-(3,5-dimethylisoxazol-4-yl)phenoxy]pyrrolidine-1-carboxylate 
• 354812-10-5 2-[(aminocarbonyl)amino]-5-bromo-3-thiophenecarboxamide 
• 1609116-59-7 [2-[(3S)-1-tert-butoxycarbonylpyrrolidin-3-yl]oxy-4-(3,5-dimethylisoxazol-4-yl)phenyl]boronic acid 
• 1609116-60-0 C₂₆H₃₇BN₂O₆ 

Relevant academic research and scientific papers

Exploiting the differential reactivities of halogen atoms: Development of a scalable route to IKK2 inhibitor AZD3264

An efficient and scalable synthesis of AZD3264 is described in which the differential reactivities of various halogen atoms have been employed. The process involves five linear chemical steps with three isolated stages starting from commercially available fragments.