16096-13-2

Basic information

• Product Name: Pyridine,2-(1-methylethoxy)-
• Synonyms: Pyridine,2-(1-methylethoxy)-;2-isopropoxypyridine;2-Isopropyloxypyridine;2-propan-2-yloxypyridine
• CAS NO: 16096-13-2
• Molecular Formula: C₈H₁₁NO
• Molecular Weight: 137.18
• Product Categories: Pyridines
• Mol File: 16096-13-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 179.5±13.0 °C(Predicted)
• Appearance: /
• Density: 0.979±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 4.29±0.12(Predicted)
• CAS DataBase Reference: Pyridine,2-(1-methylethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine,2-(1-methylethoxy)-(16096-13-2)
• EPA Substance Registry System: Pyridine,2-(1-methylethoxy)-(16096-13-2)

Safety Data

• Hazardous Substances Data: 16096-13-2(Hazardous Substances Data)

Usage

General Description

Pyridine, 2-(1-methylethoxy)- is a chemical compound with the molecular formula C8H11NO. It is a derivative of pyridine, a six-membered heterocyclic ring with five carbon atoms and one nitrogen atom. The compound contains a 2-(1-methylethoxy) group, which consists of a methyl group attached to an ethoxy group. This chemical is commonly used as an intermediate in the production of pharmaceuticals, pesticides, and other organic compounds. It is also utilized as a solvent and reagent in organic chemistry reactions. Pyridine, 2-(1-methylethoxy)- is flammable and should be handled with caution in a well-ventilated environment.

Upstream product

• 504-29-0 2-aminopyridine 
• 75-26-3 isopropyl bromide 
• 4447-60-3 Triisopropoxymethan 
• 142-08-5 2-hydroxypyridin 
• 75-30-9 2-iodo-propane 
• 109-09-1 2-chloropyridine 
• 67-63-0 isopropyl alcohol 
• 683-60-3 sodium isopropylate 

Downstream Products

• 22973-00-8 1-isopropylpyridin-2(1H)-one 
• 142-08-5 2-Pyridone 
• 187737-37-7 propene 

Relevant articles and documents

Preparation method of ortho-alkoxy substituted pyridine compound

The invention provides a preparation method of an ortho-alkoxy substituted pyridine compound, the preparation method comprises the following step: reacting an ortho-amino substituted pyridine compound with an ortho-formate compound in the presence of a nitrite compound to generate the ortho-alkoxy substituted pyridine compound. The method has the advantages of high efficiency, low cost, environmental protection and the like.

Antimycobacterial cycloartane derivatives from the roots of Trichilia welwistchii C. DC (Meliaceae)

Chemical investigation of the roots of Trichilia welwitschii yielded a cycloartane type terpenoid 28,29-bis-norcycloart-24-en-3β,4α,6α-triol (1), isolated as pure compound for the first time, three coumarins and three sterols. New cycloartane derivatives (1a) and (1b+1c) were obtained by hemi-synthetic reaction of compound 1. The structures of 1a-c were established by spectroscopic methods including 1D and 2D-NMR analysis, HR-EIMS, chemical transformations and by comparison of these data with those of related compounds. Evaluated for their antimycobacterial potential, compound 1 and 1b+1c were determined to show significant activities against Mycobacterium tuberculosis MIC values of 6.25 μg mL-1 while compound 1a displayed weak activity showing MIC > 100 μg mL-1. Compounds 2-4 displayed moderate activity with MIC values range from 12.5 to 50 μg mL-1.

Highly efficient synthesis of o-(2,4-dinitrophenyl)hydroxylamine. Application to the synthesis of substituted N-benzoyliminopyridinium ylides

An efficient two-step synthesis of O-(2,4-dinitrophenyl)hydroxylamine is described along with a comparison of its aminating efficiency with O-mesitylenesulfonylhydroxylamine (MSH). It was used in an expedient N-amination/benzoylation procedure involving various substituted pyridines, leading to polysubstituted N-benzoyliminopyridinium ylides, and the scope of its amination power was studied.