1610370-48-3

Upstream product

• 68837-59-2 4-bromo-2-methylbenzoic acid 
• 1610370-47-2 ((4S,5R)-1-(4-((2'-fluoro-5'-methoxy-3-methylbiphenyl-4-yl)methyl)phenyl)-4-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)methanol 
• 124-63-0 methanesulfonyl chloride 
• 1610370-46-1 (S)-3-((4S,5R)-1-(4-((2'-fluoro-5'-methoxy-3-methylbiphenyl-4-yl)methyl)phenyl)-4-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazole-5-carbonyl)-4-phenyloxazolidin-2-one 
• 1610370-45-0 2,2,2-trifluoro-N'-(4-((2'-fluoro-5'-methoxy-3-methylbiphenyl-4-yl)methyl)phenyl)acetohydrazonoyl chloride 
• 1610370-44-9 2,2,2-trifluoro-N'-(4-((2'-fluoro-5'-methoxy-3-methylbiphenyl-4-yl)methyl)phenyl)acetohydrazide 
• 1610370-43-8 benzyl 1-(4-((2'-fluoro-5'-methoxy-3-methylbiphenyl-4-yl)methyl)phenyl)-2-(2,2,2-trifluoroacetyl)hydrazinecarboxylate 
• 1610370-42-7 benzyl 1-(4-((2'-fluoro-5'-methoxy-3-methylbiphenyl-4-yl)methyl)phenyl)hydrazinecarboxylate 
• 1610370-41-6 2-fluoro-4'-(4-iodobenzyl)-5-methoxy-3'-methyl-1,1'-biphenyl 
• 1610370-40-5 2'-fluoro-5'-methoxy-3-methyl-[1,1'-biphenyl]-4-carbaldehyde 
• 24078-12-4 4-bromo-2-methylbenzaldehyde 
• 17100-58-2 4-bromo-2-methylbenzyl alcohol 

Downstream Products

• 1610370-50-7 methyl 2-((4S,5S)-1-(4-((2'-fluoro-5'-methoxy-3-methylbiphenyl-4-yl)methyl)phenyl)-4-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)acetate 
• 1610370-39-2 2-((4S,5S)-1-(4-((2'-fluoro-5'-methoxy-3-methylbiphenyl-4-yl)methyl)phenyl)-4-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)acetic acid 
• 1610371-18-0 ethyl 2-((4S,5S)-1-(4-((2'-fluoro-5'-methoxy-3-methyl-[1,1'-biphenyl]-4-yl)methyl)phenyl)-4-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)acetate 
• 1610371-19-1 ethyl 2-((4S,5S)-1-(4-((2'-fluoro-5'-hydroxy-3-methyl-[1,1'-biphenyl]-4-yl)methyl)phenyl)-4-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)acetate 
• 1610371-17-9 2-((4S,5S)-1-(4-((2'-fluoro-5'-hydroxy-3-methyl-[1,1'-biphenyl]-4-yl)methyl)phenyl)-4-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)acetic acid 
• 1610371-21-5 (4S,5S)-methyl 1-(4-((2'-fluoro-5'-hydroxy-3-methyl-[1,1'-biphenyl]-4-yl)methyl)phenyl)-5-(2-methoxy-2-oxoethyl)-4-methyl-4,5-dihydro-1H-pyrazole-3-carboxylate 
• 1610371-22-6 (4S,5S)-methyl 1-(4-((2'-fluoro-5'-methoxy-3-methyl-[1,1'-biphenyl]-4-yl)methyl)phenyl)-5-(2-methoxy-2-oxoethyl)-4-methyl-4,5-dihydro-1H-pyrazole-3-carboxylate 
• 1610371-68-0 2-((4S,5S)-1-(4-((5'-ethoxy-2'-fluoro-3-methyl-[1,1'-biphenyl]-4-yl)methyl)phenyl)-4-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)acetic acid 
• 1610371-69-1 ethyl 2-((4S,5S)-1-(4-((5'-ethoxy-2'-fluoro-3-methyl-[1,1'-biphenyl]-4-yl)methyl)phenyl)-4-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)acetate 
• 1610370-49-4 2-((4S,5S)-1-(4-((2'-fluoro-5'-methoxy-3-methylbiphenyl-4-yl)methyl)phenyl)-4-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)acetonitrile 

Relevant academic research and scientific papers

DIHYDROPYRAZOLE GPR40 MODULATORS

The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.