161038-68-2

Upstream product

• 459-46-1 4-Fluorobenzyl bromide 
• 223761-28-2 (4-fluorobenzyl)zinc(II) bromide 
• 4755-77-5 Ethyl oxalyl chloride 
• 95-92-1 oxalic acid diethyl ester 
• 352-11-4 1-chloromethyl-4-fluorobenzene 

Downstream Products

• 848617-63-0 (E)-(S)-5-Dibenzylamino-2-(4-fluoro-benzyl)-6-methyl-4-oxo-hept-2-enoic acid ethyl ester 
• 161038-74-0 3-(4-fluorophenyl)-α-methyl-2-<(phenylmethoxy)carbonyl>-1H-indole-1-acetic acid ethyl ester 
• 161038-69-3 2-(ethoxycarbonyl)-3-(4-fluorophenyl)-α-methyl-1H-indole-1-acetic acid phenylmethyl ester 
• 161038-75-1 2-carboxy-3-(4-fluorophenyl)-α-methyl-1H-indole-1-acetic acid ethyl ester 
• 161038-70-6 2-(ethoxycarbonyl)-3-(4-fluorophenyl)-α-methyl-1H-indole-1-acetic acid 
• 161038-73-9 3-(4-fluorophenyl)-1H-indole-2-carboxylic acid phenylmethyl ester 
• 1025829-01-9 3-(4-fluorophenyl)-1-(2-hydroxy-1-methylethyl)-1H-indole-2-carboxylic acid ethyl ester 
• 161038-77-3 3-(4-fluorophenyl)-2-hydroxymethyl-α-methyl-1H-indole-1-acetic acid ethyl ester 
• 161038-71-7 10-(4-fluorophenyl)-3,4-dihydro-4-methyl-1H-<1,4>oxazino<4,3-a>indol-1-one 
• 161038-72-8 10-(4-fluorophenyl)-3,4-dihydro-4-methyl-1H-<1,4>oxazino<4,3-a>indol-1-ol 
• 141306-66-3 3-(4-fluorophenyl)-1H-indole-2-carboxylic acid 
• 93957-39-2 3-(4-Fluorophenyl)-1H-indole-2-carboxylic acid,ethyl ester 

Relevant academic research and scientific papers

ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF

Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting arginine methyltransferase activity. Methods of using the compo

Fused lactones as a route to functionalized 1-substituted indoles

Indole lactones 8 and 14 were synthesized as a means of functionalizing the 1-isopropyl substituent of the indole nucleus. Lactone 8, upon reduction with diisobutylaluminum hydride, produces lactol 9 which behaves like a masked hydroxy aldehyde and underg