161038-69-3

Upstream product

• 100-63-0 phenylhydrazine 
• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 161038-68-2 4-fluoro-α-oxobenzenepropanoic acid ethyl ester 

Downstream Products

• 161038-70-6 2-(ethoxycarbonyl)-3-(4-fluorophenyl)-α-methyl-1H-indole-1-acetic acid 
• 161038-72-8 10-(4-fluorophenyl)-3,4-dihydro-4-methyl-1H-<1,4>oxazino<4,3-a>indol-1-ol 
• 161038-71-7 10-(4-fluorophenyl)-3,4-dihydro-4-methyl-1H-<1,4>oxazino<4,3-a>indol-1-one 
• 1025829-01-9 3-(4-fluorophenyl)-1-(2-hydroxy-1-methylethyl)-1H-indole-2-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Fused lactones as a route to functionalized 1-substituted indoles

Indole lactones 8 and 14 were synthesized as a means of functionalizing the 1-isopropyl substituent of the indole nucleus. Lactone 8, upon reduction with diisobutylaluminum hydride, produces lactol 9 which behaves like a masked hydroxy aldehyde and underg