1610838-89-5

Basic information

• Product Name: (R)-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofuran-5-yl)(2-nitrophenyl)methanone
• CAS NO: 1610838-89-5
• Molecular Weight: 378.428
• Mol File: 1610838-89-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofuran-5-yl)(2-nitrophenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofuran-5-yl)(2-nitrophenyl)methanone(1610838-89-5)
• EPA Substance Registry System: (R)-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofuran-5-yl)(2-nitrophenyl)methanone(1610838-89-5)

Safety Data

• Hazardous Substances Data: 1610838-89-5(Hazardous Substances Data)

Upstream product

• 73376-03-1 (4-methoxyphenyl)(2-nitrophenyl)methanone 
• 610-14-0 2-nitrobenzyl chloride 
• 100-66-3 methoxybenzene 
• 765-38-8 (R)-(-)-2-methylpyrrolidine 
• 1610838-87-3 (4-hydroxy-3-iodophenyl)(2-nitrophenyl)methanone 
• 460747-73-3 (R)-1-(but-3-yn-1-yl)-2-methylpyrrolidine 

Relevant articles and documents

Synthesis and biological evaluation of XB-1 analogues as novel histamine H3 receptor antagonists and neuroprotective agents

A novel class of H3 receptor antagonists, XB-1 analogues based on benzophenone or oxydibenzene scaffolds were synthesized, and their biological activities were evaluated to determine their in vitro neuroprotective effects against Aβ25-35-induced damage in primary cortical neurons and against glutamate-induced neuronal injury in primary cerebellar granule neurons. The results indicated that all of the tested analogues displayed neuroprotective activity at 0.1 μM or 1 μM. These findings may provide new insights into the development of novel promising H3 receptor antagonists with potential neuroprotective activity.