73376-03-1

Basic information

• Product Name: (4-METHOXYPHENYL)(2-NITROPHENYL)METHANONE
• Synonyms: (4-METHOXYPHENYL)(2-NITROPHENYL)METHANONE
• CAS NO: 73376-03-1
• Molecular Formula: C₁₄H₁₁NO₄
• Molecular Weight: 0
• Mol File: 73376-03-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4-METHOXYPHENYL)(2-NITROPHENYL)METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-METHOXYPHENYL)(2-NITROPHENYL)METHANONE(73376-03-1)
• EPA Substance Registry System: (4-METHOXYPHENYL)(2-NITROPHENYL)METHANONE(73376-03-1)

Safety Data

• Hazardous Substances Data: 73376-03-1(Hazardous Substances Data)

Upstream product

• 552-16-9 ortho-nitrobenzoic acid 
• 100-66-3 methoxybenzene 
• 407-25-0 trifluoroacetic anhydride 
• 610-14-0 2-nitrobenzyl chloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 609-73-4 o-nitroiodobenzene 
• 100476-07-1 (4-methoxy-phenyl)-(2-nitro-phenyl)-methanol 

Downstream Products

• 61101-88-0 (4-hydroxyphenyl)(2-nitrophenyl)methanone 
• 1610838-87-3 (4-hydroxy-3-iodophenyl)(2-nitrophenyl)methanone 
• 1610838-89-5 (R)-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofuran-5-yl)(2-nitrophenyl)methanone 
• 1446099-59-7 (4-(3-chloropropoxy)phenyl)(2-nitrophenyl)methanone 
• 1446099-55-3 (4-(2-chloroethoxy)phenyl)(2-nitrophenyl)methanone 
• 1446099-49-5 (R)-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)(2-nitrophenyl)methanone 
• 1446099-45-1 (R)-(4-(2-(2-methylpyrrolidin-1-yl)ethoxy)phenyl)(2-nitrophenyl)methanone 
• 100476-07-1 (4-methoxy-phenyl)-(2-nitro-phenyl)-methanol 
• 106015-78-5 2-{4-[4-(4-Methoxy-phenyl)-quinolin-2-yl]-piperazin-1-yl}-ethanol 
• 106015-61-6 2-(4-Ethyl-piperazin-1-yl)-4-(4-methoxy-phenyl)-quinoline 
• 120301-15-7 4-(4-Methoxy-phenyl)-2-piperazin-1-yl-quinoline 
• 37118-72-2 4-(p-methoxyphenyl)-2-(1H)-quinolinone 
• 36188-55-3 N-(2-(4-methoxybenzoyl)phenyl)acetamide 
• 37118-73-3 2-chloro-4-(4-methoxyphenyl)quinoline 

Relevant articles and documents

Synthesis and biological evaluation of XB-1 analogues as novel histamine H3 receptor antagonists and neuroprotective agents

A novel class of H3 receptor antagonists, XB-1 analogues based on benzophenone or oxydibenzene scaffolds were synthesized, and their biological activities were evaluated to determine their in vitro neuroprotective effects against Aβ25-35-induced damage in primary cortical neurons and against glutamate-induced neuronal injury in primary cerebellar granule neurons. The results indicated that all of the tested analogues displayed neuroprotective activity at 0.1 μM or 1 μM. These findings may provide new insights into the development of novel promising H3 receptor antagonists with potential neuroprotective activity.

Cascade synthesis of 3-quinolinecarboxylic ester via benzylation/ propargylation-cyclization

(Chemical Equation Presented) Reactions of 2-amino-aryl alcohols with β-ketoesters catalyzed by a catalytic amout of FeCl3 via tandem benzylation-cyclization produce the corresponding 3-quinolinecarboxylic esters in good to high yields. Extending this methodology to propargylation- cyclization, 2-nitrophenyl propargyl alcohols with β-ketoesters catalyzed by FeCl3 and SnCl2 also produce the 4-alkyne-3- quinolinecarboxylic esters. The mechanistic details of this benzylation/ propargylation and cyclization cascade process are also discussed.

Synthesis of 1H-indazoles by reductive cyclization of o-nitro-ketoximes

ortho-Nitro-ketoximes are converted to 1H-indazoles upon reaction with carbon monoxide with [Cp*Fe(CO)2]2 as catalyst.

Benzophenones and benzhydrols

Compounds having the formula STR1 WHERE X is --CO-- or --CHOH--, Y and Z are halogen, alkyl, trifluoromethyl, alkoxy, hydroxy, nitro, cyano, carboxy, carbalkoxy, carbamoyl, or alkylthio, and m and n are 0, 1, or 2 Are useful in controlling undesirable secondary growth in plants, particularly sucker growth in tobacco.