16111-22-1

Basic information

• Product Name: 2-(3-oxo-1,3-diphenylpropylsulfanyl)acetic acid
• Synonyms: 2-(3-oxo-1,3-diphenylpropylsulfanyl)acetic acid
• CAS NO: 16111-22-1
• Molecular Weight: 300.378
• Mol File: 16111-22-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(3-oxo-1,3-diphenylpropylsulfanyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-oxo-1,3-diphenylpropylsulfanyl)acetic acid(16111-22-1)
• EPA Substance Registry System: 2-(3-oxo-1,3-diphenylpropylsulfanyl)acetic acid(16111-22-1)

Safety Data

• Hazardous Substances Data: 16111-22-1(Hazardous Substances Data)

Upstream product

• 611-91-6 2,3-dibromo-1,3-diphenylpropane-1-one 
• 367-51-1 disodium thioglycolate 
• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 68-11-1 mercaptoacetic acid 
• 94-41-7 benzalacetophenone 
• 614-47-1 1,3-diphenyl-propen-3-one 

Downstream Products

• 68-11-1 mercaptoacetic acid 
• 614-47-1 1,3-diphenyl-propen-3-one 

Relevant articles and documents

Amino acid catalyzed thio-Michael addition reactions

Using amino acid as a catalyst, an inexpensive, nontoxic, environmentally friendly, metal-free reaction procedure for C-S bond formation via thio-Michael addition reaction has been developed. The thio-Michael addition products were obtained in excellent yields under mild and neutral conditions. This metal-free catalytic protocol was found to be a good alternative to the existing metal catalyst methodology for the thio-Michael addition reaction.

Synthesis of Carboxylic Acid Derivatives of Dihydrochalcones

Reaction of chalcones 1-8 with thioglycolic acid, 3-mercaptopropionic acid or thiosalicylic acid gives dihydrochalcone derivatives 9-23.