16111-22-1Relevant academic research and scientific papers
Amino acid catalyzed thio-Michael addition reactions
Kumar, Atul,Akanksha
, p. 11086 - 11092 (2007)
Using amino acid as a catalyst, an inexpensive, nontoxic, environmentally friendly, metal-free reaction procedure for C-S bond formation via thio-Michael addition reaction has been developed. The thio-Michael addition products were obtained in excellent yields under mild and neutral conditions. This metal-free catalytic protocol was found to be a good alternative to the existing metal catalyst methodology for the thio-Michael addition reaction.
Synthesis and in vitro antimicrobial activity of novel 2-(3-oxo-1,3- diarylpropylthio)acetic acid derivatives
Gezegen, Hayreddin,Karaman, Isa,Ceylan, Mustafa,Dilmac, Merve
, p. 893 - 900 (2012/10/30)
A series of novel 2-(3-oxo-1,3-diarylpropylthio)acetic acid derivatives (3a-l) were prepared by base catalyzed addition of thioglycolic acid to chalcones (1a-l). The antibacterial activities of synthesized compounds were screened against human pathogenic microorganisms by employing the disk-diffusion technique. For the active compounds, also minimum inhibitory concentrations (MICs) were determined.
Synthesis of Carboxylic Acid Derivatives of Dihydrochalcones
Levai, Albert
, p. 127 - 129 (2007/10/02)
Reaction of chalcones 1-8 with thioglycolic acid, 3-mercaptopropionic acid or thiosalicylic acid gives dihydrochalcone derivatives 9-23.
