161173-98-4

Usage

Uses

Used in Organic Synthesis:
4-(3-Bromophenyl)but-1-ene is used as a key intermediate in organic synthesis for the production of a variety of compounds. Its unique structure allows it to be a versatile building block in the creation of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 4-(3-Bromophenyl)but-1-ene is utilized as an intermediate in the synthesis of various drugs. Its presence in these processes is crucial for the development of new medications that can address a range of health conditions.
Used in Agrochemical Production:
Similarly, in agrochemical manufacturing, 4-(3-Bromophenyl)but-1-ene serves as an intermediate. It contributes to the development of products designed to enhance crop protection and improve agricultural yields.
Used as a Reagent in Chemical Reactions:
4-(3-Bromophenyl)but-1-ene is also employed as a reagent in a range of chemical reactions aimed at producing other organic compounds. Its reactivity makes it a valuable component in advancing chemical research and development.
Safety Considerations:

InChI:InChI=1/C10H11Br/c1-2-3-5-9-6-4-7-10(11)8-9/h2,4,6-8H,1,3,5H2

Upstream product

• 823-78-9 meta-bromobenzyl bromide 
• 2622-05-1 allylmagnesium bromide 
• 210115-30-3 3-(3-bromophenyl)propanal 
• 19493-09-5 Methylenetriphenylphosphorane 
• 65537-54-4 3-(3-bromophenyl)-propan-1-ol 
• 42287-90-1 3-(3-bromophenyl)propanoic acid 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 1730-25-2 allylmagnesium bromide 

Downstream Products

• 358751-04-9 1-(3-but-3-enyl-phenyl)-ethanone 
• 218153-01-6 4-(3-bromophenyl)butan-1-ol 
• 109757-62-2 1-bromo-3-(4-bromobutyl)benzene 
• 1426943-39-6 2-(4-(3-bromophenyl)butyl)isoindoline-1,3-dione 
• 1567213-68-6 (2S)-methyl 2-(7-(4-allyl-5-chloro-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-2-(3‘-(but-3-en-1-yl)-[1,1‘-biphenyl]-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate 
• 1567213-91-5 (2S)-methyl 2-(7-(4-allyl-5-chloro-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-2-(2’-(but-3-en-1-yl)-[1,1’-biphenyl]-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate 
• 1567213-64-2 2-(3-(but-3-en-1-yl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1567213-86-8 dimethyl (2-(but-3-en-1-yl)phenyl)boronate 
• 1097734-01-4 (3-(but-3-en-1-yl)phenyl)methanol 
• 358751-00-5 3-(but-3-en-1-yl)benzaldehyde 
• 54887-20-6 1-bromo-3-n-butylbenzene 
• 931430-15-8 1-bromo-3-(3-fluoro-4-iodo-butyl)-benzene 

Relevant academic research and scientific papers

Enantioselective Intermolecular C-H Amination Directed by a Chiral Cation

The enantioselective amination of C(sp3)-H bonds is a powerful synthetic transformation yet highly challenging to achieve in an intermolecular sense. We have developed a family of anionic variants of the best-in-class catalyst for Rh-catalyzed C-H amination, Rh2(esp)2, with which we have associated chiral cations derived from quaternized cinchona alkaloids. These ion-paired catalysts enable high levels of enantioselectivity to be achieved in the benzylic C-H amination of substrates bearing pendant hydroxyl groups. Additionally, the quinoline of the chiral cation appears to engage in axial ligation to the rhodium complex, providing improved yields of product versus Rh2(esp)2 and highlighting the dual role that the cation is playing. These results underline the potential of using chiral cations to control enantioselectivity in challenging transition-metal-catalyzed transformations.

Access to Trisubstituted Fluoroalkenes by Ruthenium-Catalyzed Cross-Metathesis

Although the olefin metathesis reaction is a well-known and powerful strategy to get alkenes, this reaction remained highly challenging with fluororalkenes, especially the Cross-Metathesis (CM) process. Our thought was to find an easy accessible, convenient, reactive and post-functionalizable source of fluoroalkene, that we found as the methyl 2-fluoroacrylate. We reported herein the efficient ruthenium-catalyzed CM reaction of various terminal and internal alkenes with methyl 2-fluoroacrylate giving access, for the first time, to trisubstituted fluoroalkenes stereoselectively. Unprecedent TON for CM involving fluoroalkene, up to 175, have been obtained and the reaction proved to be tolerant and effective with a large range of olefin partners giving fair to high yields in metathesis products. (Figure presented.).

Remote migratory cross-electrophile coupling and olefin hydroarylation reactions enabled by in situ generation of nih

A highly efficient strategy for remote reductive cross-electrophile coupling has been developed through the ligand-controlled nickel migration/arylation. This general protocol allows the use of abundant and bench-stable alkyl bromides and aryl bromides for the synthesis of a wide range of structurally diverse 1, 1-diarylalkanes in excellent yields and high regioselectivities under mild conditions. We also demonstrated that alkyl bromide could be replaced by the proposed olefin intermediate while using n-propyl bromide/Mn0 as a potential hydride source.

Pyrazolopyrimidine Macrocycles as Inhibitors of Human Immunodeficiency Virus Replication

The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compound

MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO

This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containing such molecules,

AMINO-5-[4-(DIFLUOROMETHOXY)-PHENYL]-5-PHENYLIMIDAZOLONE COMPOUNDS FOR THE INHIBITION OF BETA-SECRETASE

The present invention provides a 2-amino-5-[4-(difluoromethoxy)phenyl]-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.