358751-00-5Relevant academic research and scientific papers
Remote migratory cross-electrophile coupling and olefin hydroarylation reactions enabled by in situ generation of nih
Chen, Fenglin,Chen, Ke,Zhang, Yao,He, Yuli,Wang, Yi-Ming,Zhu, Shaolin
supporting information, p. 13929 - 13935 (2017/11/07)
A highly efficient strategy for remote reductive cross-electrophile coupling has been developed through the ligand-controlled nickel migration/arylation. This general protocol allows the use of abundant and bench-stable alkyl bromides and aryl bromides for the synthesis of a wide range of structurally diverse 1, 1-diarylalkanes in excellent yields and high regioselectivities under mild conditions. We also demonstrated that alkyl bromide could be replaced by the proposed olefin intermediate while using n-propyl bromide/Mn0 as a potential hydride source.
Pyrazolopyrimidine Macrocycles as Inhibitors of Human Immunodeficiency Virus Replication
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Paragraph 0364, (2015/09/22)
The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compound
Synthesis of xanthenes, Indanes, and tetrahydronaphthalenes via intramolecular phenyl-carbonyl coupling reactions
Kuo, Chih-Wei,Fang, Jim-Min
, p. 877 - 892 (2007/10/03)
Benzaldehydes and acetophenones bearing tethered carbonyl chains underwent the intramolecular phenyl-carbonyl coupling reactions, by mediation of samarium diiodide and hexamethylphosphoramide, to afford the xanthenes and fused benzocarbocyclic compounds c
