1612138-71-2

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 1708-40-3 2-phenyl-[1,3]dioxan-5-ol 
• 1374632-99-1 (2R,3S,4R,5S)-4-(tert-butyldiphenylsilyloxy)-2-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-5-(p-tolylthio)tetrahydrofuran-3-ol 
• 1374633-02-9 (2S,3S,4R,5S)-4-(tert-butyldiphenylsilyloxy)-2-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-5-(p-tolylthio)tetrahydrofuran-3-yl 4-oxopentanoate 
• 1374633-03-0 (2S,3R,4R,5S)-2-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-hydroxy-5-(p-tolylthio)tetrahydrofuran-3-yl 4-oxopentanoate 
• 1374633-04-1 (2S,3S,4R,5S)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-(4-oxopentanoyloxy)-2-(p-tolyl-thio)tetrahydrofuran-3-yl benzoate 
• 1612138-70-1 (2R,3R,4S,5S)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-(4-oxopentanoyloxy)-2-(2-phenyl-1,3-dioxan-5-yloxy)tetrahydrofuran-3-yl benzoate 
• 920267-56-7 4-methylphenyl 1-thio-β-D-galactofuranoside 
• 848900-41-4 p-tolyl 5,6-O-isopropylidene-1-thio-β-D-galactofuranoside 

Downstream Products

• 1612138-69-8 (2S,3S,4R,5S)-2-((2S,3S,4R,5R)-4-(benzoyloxy)-2-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-5-(2-phenyl-1,3-dioxan-5-yloxy)tetrahydrofuran-3-yloxy)-5-((R)-1,2-bis(benzoyloxy)ethyl)tetrahydrofuran-3,4-diyl dibenzoate 

Relevant academic research and scientific papers

Total synthesis of fuzinoside

The first total syntheses of fuzinoside (1b) were achieved from d-galactose through two strategies (BCA and ABC) in 11 (total yield: 5.0%) and 15 (total yield: 3.7%) steps, respectively. Comparison of NMR data of synthetic compound 1b and those of the fuzinoside isolated from the lateral roots of Aconitum carmicaelii suggests that the structure reported in the literature1,2 might not be accurate. The synthetic fuzinoside (1b) exhibited moderate cardiac activity in the isolated bullfrog heart assay.