1612240-17-1

Basic information

• Product Name: 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-ol
• Synonyms: 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-ol
• CAS NO: 1612240-17-1
• Molecular Weight: 226.275
• Mol File: 1612240-17-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-ol(1612240-17-1)
• EPA Substance Registry System: 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-ol(1612240-17-1)

Safety Data

• Hazardous Substances Data: 1612240-17-1(Hazardous Substances Data)

Upstream product

• 591-20-8 3-Bromophenol 
• 100-44-7 benzyl chloride 
• 95-56-7 2-hydroxybromobenzene 
• 100-39-0 benzyl bromide 
• 53087-13-1 3-(benzyloxy)phenyl bromide 
• 675825-21-5 Lithium enolate of the acetaldehyde 
• 24318-02-3 1-(benzyloxy)-3-chlorobenzene 
• 169615-68-3 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-one 
• 31575-75-4 2-bromophenyl benzyl ether 

Downstream Products

• 169615-68-3 5-(benzyloxy)bicyclo[4.2.0]octa-1⁽⁶⁾,2,4-trien-7-one 

Relevant articles and documents

Effect of Ring Functionalization on the Reaction Temperature of Benzocyclobutene Thermoset Polymers

The temperature required to induce cross-linking in typical benzocyclobutene-based thermosets is near 250 °C, which exceeds the use temperature of many chemical components. A new and versatile synthesis of BCB-functionalized monomers has allowed access to monomers that can be incorporated into a variety of macromolecular platforms to enable significantly reduced cure temperatures. Incorporation of BCB-functionalized comonomers in polystyrene and polynorbornene enabled insolublization of thin films by curing at only 120 °C for 1 h.

Skeleton Reorganization of Substituted Benzocyclobutenols through Rh-Catalyzed C-C Bond Cleavage Manipulated by Hydrogen Transfer

Although transition-metal-catalyzed C-C bond activation has been investigated extensively, C-C bond cleavage manipulated by hydrogen transfer has been unexplored. In this work, we disclose a skeleton reorganization of alkene-tethered benzocyclobutenols through Rh-catalyzed C-C bond cleavage coupled with intra- and intermolecular hydrogen transfer. The reaction pathway was well-tuned by the catalytic systems. As a result, divergent benzofurans bearing 4-β-hydroxy or 4-β-keto moieties were synthesized under pH- and redox-neutral conditions.

MODULATORS OF THR-β AND METHODS OF USE THEREOF

Disclosed herein are compounds of Formula (I) or a pharmaceutically acceptable salt, prodrug, amide or ester thereof, where i) TL is a moiety of Formula IlIa, lIIb, IlIa, IIIb, IIIc, or IIId; ii) CE is a moiety of Formula IV; iii) HD is a moiety of Formula V or VI; where the substituents are as defined herein. Disclosed are also pharmaceutical compositions comprising the above compounds, and methods of treating disease by administering or contact a patient with one or more of the above compounds.