161226-80-8Relevant articles and documents
Nanoscale molecular rods with a new building block for solubility enhancement
Wessig, Pablo,Moellnitz, Kristian
, p. 4452 - 4457 (2008/09/21)
(Chemical Equation Presented) A new building block bearing a [1,3]dioxolo[4,5-f][1,3]benzodioxole core was developed to enhance the solubility of molecular rods by lateral alkyl chains. On incorporation in molecular rods with oligospiroketal structure, the straight geometry is retained, which was concluded from the X-ray crystal structure analysis of one of the rods. The determination of the solubility of a collection of rods bearing this building block revealed that already a butyl group efficiently hinders the aggregation of the rods and consequently causes a considerable enhancement of the solubility. Piperidine rings are located at the ends of the rods, which offer the opportunity for versatile functionalization. Thus, an N,N′-bis(azidoacetyl)-functionalized rod was prepared, which could serve as rigid linkage, initiated by a "Click" reaction.
An efficient one-pot synthesis of 1,4-diacyl-2,3,5,6-tetramethoxybenzenes via biscuprated precursors
Bringmann,Geuder,Harmsen
, p. 1143 - 1145 (2007/10/02)
The efficient double acylation of 1,2,4,5-tetramethoxybenzene via the corresponding dicopper species is described; this reaction could not be attained either via the corresponding dilithium salts, or by Friedel-Crafts reaction. According to our method, the hitherto unknown diketones 1a and 1b are obtained in only one step in good yields. Further synthetic access to the compound Ia is realized by bismethylation of the corresponding terephthaloyl dichloride 7.