6172-64-1Relevant academic research and scientific papers
An efficient one-pot synthesis of 1,4-diacyl-2,3,5,6-tetramethoxybenzenes via biscuprated precursors
Bringmann,Geuder,Harmsen
, p. 1143 - 1145 (1994)
The efficient double acylation of 1,2,4,5-tetramethoxybenzene via the corresponding dicopper species is described; this reaction could not be attained either via the corresponding dilithium salts, or by Friedel-Crafts reaction. According to our method, the hitherto unknown diketones 1a and 1b are obtained in only one step in good yields. Further synthetic access to the compound Ia is realized by bismethylation of the corresponding terephthaloyl dichloride 7.
