16130-32-8

Basic information

• Product Name: (4-chlorophenyl)(3-(2-hydroxyethyl)-5-methoxy-2-methyl-1H-indol-1-yl)methanone
• Synonyms: (4-chlorophenyl)(3-(2-hydroxyethyl)-5-methoxy-2-methyl-1H-indol-1-yl)methanone
• CAS NO: 16130-32-8
• Molecular Weight: 343.81
• Mol File: 16130-32-8.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: (4-chlorophenyl)(3-(2-hydroxyethyl)-5-methoxy-2-methyl-1H-indol-1-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chlorophenyl)(3-(2-hydroxyethyl)-5-methoxy-2-methyl-1H-indol-1-yl)methanone(16130-32-8)
• EPA Substance Registry System: (4-chlorophenyl)(3-(2-hydroxyethyl)-5-methoxy-2-methyl-1H-indol-1-yl)methanone(16130-32-8)

Safety Data

• Hazardous Substances Data: 16130-32-8(Hazardous Substances Data)

Upstream product

• 191348-14-8 2-iodo-4-methoxylaniline 
• 122-01-0 4-chloro-benzoyl chloride 
• 873657-14-8 N-(4-chlorobenzoyl)-2-iodo-4-methoxyaniline 
• 873657-15-9 3-(tert-butyldimethylsiloxy)ethyl-1-(4-chlorobenzoyl)-5-methoxy-2-methylindole 
• 53-86-1 [1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid 

Downstream Products

• 138561-27-0 C₂₉H₃₅ClN₂O₇ 
• 910457-38-4 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}ethyl methanesulfonate 
• 1414702-04-7 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)ethyl 2-(1H-pyrrol-3-yl)acetate 
• 1376615-38-1 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetaldehyde O-methyl oxime 
• 1376615-37-0 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetaldehyde oxime 
• 138561-28-1 N-{2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-1-ethyl}hydroxylamine 
• 53-86-1 [1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid 
• 1026313-08-5 C₃₀H₃₁ClN₄O₆S 
• 24438-49-1 <1-(4-chlorobenzoyl)-2-methyl-5-methoxyindol-3-yl>acetaldehyde 
• 22789-46-4 1-(4-chlorobenzoyl)-3-ethyl-5-methoxy-2-methylindole 

Relevant articles and documents

The aldehyde analog of indomethacin.

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SYNTHESIS OF DEUTERATED ALDEHYDES

Described are methods for preparing a deuterated aldehyde using N-heterocyclic carbene catalysts in a solvent comprising D2O. The methods may be used to convert a wide variety of aldehydes (e.g., aryl, alkyl, or alkenyl aldehydes) to C-1 deuterated aldehydes under mild reaction conditions without functionality manipulation.

Silver-Promoted Direct Phosphorylation of Bulky C(sp2)-H Bond to Build Fully Substituted β-Phosphonodehydroamino Acids

A general and practical cross-dehydrogenative coupling protocol between readily available trisubstituted α,β-dehydro α-amino carboxylic esters and H-phosphites is described. This C(sp2)-H phosphorylation reaction proceeds with absolute Z-selectivity promoted by silver salt in a radical relay manner. The bulky tetrasubstituted β-phosphonodehydroamino acids were obtained in grams and added new modules to the toolkit for peptide modifications.