161302-92-7Relevant academic research and scientific papers
GLYCOHYDROLASE INHIBITORS, THEIR PREPARATION AND USE THEREOF
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, (2008/06/13)
A compound of the formula, wherein n, m, and p, which may be the same or different, are a number between 0 and 5; q is a number between 0 and 10; R1, R2 R3 R4 and R5, which may be the same or different, are a hydrogen, a hydroxyl, a halogen, a hydrocarbon
Synthesis of Isofagomine, a Novel Glycosidase Inhibitor
Jespersen, Tina M.,Bols, Mikael,Sierks, Michael R.,Skrydstrup, Troels
, p. 13449 - 13460 (2007/10/02)
(3R, 4R, 5R)-3,4-Dihydroxy-5-hydroxymethyl-piperidine (Isofagomine, 1) a potent β-glucosidase inhibitor was synthesised in a 6 step synthesis in an overall yield of 34percent starting from 1,6:2,3-dianhydro-4-O-benzyl-β-D-mannopyranose (7).A hydroxymethyl
