161302-91-6Relevant academic research and scientific papers
Synthesis of Isofagomine, a Novel Glycosidase Inhibitor
Jespersen, Tina M.,Bols, Mikael,Sierks, Michael R.,Skrydstrup, Troels
, p. 13449 - 13460 (2007/10/02)
(3R, 4R, 5R)-3,4-Dihydroxy-5-hydroxymethyl-piperidine (Isofagomine, 1) a potent β-glucosidase inhibitor was synthesised in a 6 step synthesis in an overall yield of 34percent starting from 1,6:2,3-dianhydro-4-O-benzyl-β-D-mannopyranose (7).A hydroxymethyl
