161302-88-1

Upstream product

• 129797-11-1 1,6-anhydro-4-O-benzyl-2-deoxy-2-C-vinyl-β-D-glucopyranose 
• 33208-47-8 4-O-benzyl-1,6:2,3-dianhydro-β-D-mannopyranose 
• 1208102-36-6 C₁₆H₂₀O₄ 

Downstream Products

• 171499-89-1 1,6-anhydro-3,4-di-O-benzyl-2-C-benzyloxymethyl-2-deoxy-β-D-glucopyranose 
• 161302-92-7 (3R,4R,5R)-3-benzyloxy-4-hydroxy-5-hydroxymethyl-piperidine 
• 161302-91-6 4-O-benzyl-2-deoxy-2-C-hydroxymethyl-D-xylo-pentodialdose 

Relevant academic research and scientific papers

Synthesis of Isofagomine, a Novel Glycosidase Inhibitor

(3R, 4R, 5R)-3,4-Dihydroxy-5-hydroxymethyl-piperidine (Isofagomine, 1) a potent β-glucosidase inhibitor was synthesised in a 6 step synthesis in an overall yield of 34percent starting from 1,6:2,3-dianhydro-4-O-benzyl-β-D-mannopyranose (7).A hydroxymethyl

Synthesis and glycosidase inhibitory activity of noeurostegine - A new and potent inhibitor of β-glucoside hydrolases

A new, stable hemi-aminal nor-tropane christened noeurostegine was synthesised in 22 steps from levoglucosan and tested for inhibitory activity against glycoside hydrolases. Sweet almond and Thermotoga maritimaβ- glucosidases, coffee bean α-galactosidase,

Design and synthesis of 2-acetamidomethyl derivatives of isofagomine as potential inhibitors of human lysosomal β-hexosaminidases

As part of a program towards the development of specific inhibitors of human lysosomal β-hexosaminidase for use as chemical chaperones in therapy of GM2 gangliosidosis related diseases, the synthesis of 2-acetamidomethyl derivatives of isofagom