1614-34-2

Basic information

• Product Name: N-[3-(carbamothioylamino)phenyl]acetamide
• Synonyms: acetamide, N-[3-[(aminothioxomethyl)amino]phenyl]-; N-[3-(Carbamothioylamino)phenyl]acetamide
• CAS NO: 1614-34-2
• Molecular Formula: C₉H₁₁N₃OS
• Molecular Weight: 209.2681
• Mol File: 1614-34-2.mol
• Article Data: 1

Chemical Properties

• Density: 1.389g/cm³
• Refractive Index: 1.743
• CAS DataBase Reference: N-[3-(carbamothioylamino)phenyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-(carbamothioylamino)phenyl]acetamide(1614-34-2)
• EPA Substance Registry System: N-[3-(carbamothioylamino)phenyl]acetamide(1614-34-2)

Safety Data

• Hazardous Substances Data: 1614-34-2(Hazardous Substances Data)

Upstream product

• 3137-83-5 meta-acetamidophenyl isothiocyanate 
• 102-28-3 m-acetamide aniline 
• 108-45-2 m-phenylenediamine 
• 99-09-2 3-nitro-aniline 

Downstream Products

• 1222343-31-8 C₁₇H₁₄ClN₃OS 

Relevant articles and documents

Synthesis and in-vitro evaluation of 2-amino-4-arylthiazole as inhibitor of 3D polymerase against foot-and-mouth disease (FMD)

Foot-and-mouth disease (FMD) is a highly contagious vesicular disease of livestock caused by a highly variable RNA virus, foot-and-mouth disease virus (FMDV). One of the targets to suppress expansion of and to control FMD is 3D polymerase (FMDV 3Dpol). In this study, 2-amino-4-arylthiazole derivatives were synthesized and evaluated for their inhibitory activity against FMDV 3Dpol. Among them, compound 20i exhibited the most potent functional inhibition (IC50 = 0.39μM) of FMDV 3D polymerase and compound 24a (EC50=13.09 μM) showed more potent antiviral activity than ribavirin (EC50=1367 μM) and T1105 (EC50=347 μM) with IBRS-2 cells infected by the FMDV O/SKR/2010 strain.