16143-84-3 Usage
Description
3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE is a chemical compound that belongs to the class of acetanilides. It is a white solid with a molecular formula C10H8F6N2O and a molecular weight of 286.17 g/mol. 3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE is characterized by the presence of trifluoromethyl groups, which contribute to its unique properties and applications in various fields.
Uses
Used in Organic Synthesis:
3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE is used as a building block in organic synthesis for its versatile reactivity and the introduction of trifluoromethyl groups into target molecules. The trifluoromethyl groups enhance the lipophilicity and metabolic stability of the synthesized compounds, making them more suitable for pharmaceutical applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE is used as a valuable reagent in the synthesis of various pharmaceuticals and agrochemicals. Its trifluoromethyl groups impart unique properties to the synthesized compounds, such as increased potency, selectivity, and bioavailability, which are crucial for the development of effective drugs.
Used in Drug Development:
3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE is used as a potential candidate for drug development due to its anti-inflammatory and analgesic properties. The presence of trifluoromethyl groups in the molecule may contribute to its therapeutic effects, making it a promising candidate for the treatment of various inflammatory and painful conditions.
Used in Chemical Reactions:
Due to its high thermal stability and resistance to oxidation, 3,5-BIS(TRIFLUOROMETHYL)ACETANILIDE is used as a valuable reagent in various chemical reactions. Its robustness allows for its use in harsh reaction conditions, facilitating the synthesis of complex molecules and improving the overall efficiency of the reaction process.
Check Digit Verification of cas no
The CAS Registry Mumber 16143-84-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,1,4 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 16143-84:
(7*1)+(6*6)+(5*1)+(4*4)+(3*3)+(2*8)+(1*4)=93
93 % 10 = 3
So 16143-84-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H7F6NO/c1-5(18)17-8-3-6(9(11,12)13)2-7(4-8)10(14,15)16/h2-4H,1H3,(H,17,18)
16143-84-3Relevant articles and documents
AN ACTIVITY-GUIDE MAP OF ELECTROPHILE-CYSTEINE INTERACTIONS IN PRIMARY HUMAN IMMUNE CELLS
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Paragraph 0250-0251; 0267, (2021/04/23)
Disclosed herein are methods, pharmaceutical compositions, and vaccines for modulating an immune response. Also disclosed herein are methods, pharmaceutical compositions, and vaccines for inducing an immune response.
KOtBu-Promoted Transition-Metal-Free Transamidation of Primary and Tertiary Amides with Amines
Ghosh, Tridev,Jana, Snehasish,Dash, Jyotirmayee
supporting information, p. 6690 - 6694 (2019/09/12)
This work discloses transamidation of primary and tertiary amides with a range of aryl, heteroaryl, and aliphatic amines using potassium tert-butoxide. The reaction proceeds at room temperature under transition-metal-free conditions providing secondary amides in high yields. Moreover, reaction of cyclopropyl amine with tertiary amides proceeds with ring-opening to provide a rapid access to enamides.
COMPOSITIONS AND METHODS OF MODULATING IMMUNE RESPONSE
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Paragraph 0318; 0329; 0334, (2018/01/17)
Disclosed herein are methods, pharmaceutical compositions, and vaccines for modulating an immune response. Also disclosed, herein are methods, pharmaceutical compositions, and vaccines for inducing an immune response.
