16147-09-4

Upstream product

• 10272-07-8 3.5-dimethoxyaniline 
• 25245-27-6 1-iodo-3,5-dimethoxybenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 15994-96-4 2,4-dimethoxy-6-nitro-benzaldehyde 
• 4885-02-3 Dichloromethyl methyl ether 

Downstream Products

• 1307285-89-7 (-)-(R)-but-3-en-2-yl 6-(hept-6-en-1-yl)-2,4-dimethoxybenzoate 
• 1307285-90-0 6-(hept-6-en-1-yl)-2,4-dimethoxybenzoyl fluoride 
• 1307285-92-2 6-(hept-6-en-1-yl)-2,4-dimethoxybenzoic acid 
• 1307285-91-1 6-(hept-6-en-1-yl)-2,4-dimethoxybenzaldehyde 
• 1216818-10-8 C₂₀H₂₇NO₇ 
• 1216817-96-7 C₂₀H₂₇NO₇ 

Relevant academic research and scientific papers

Total synthesis of masked Alternaria mycotoxins - Sulfates and glucosides of alternariol (AOH) and alternariol-9-methyl ether (AME)

The synthesis of different protected alternariol derivatives using intramolecular cyclization of iodoresorcylic acid phenyl esters by palladium-catalyzed C-H activation as key step is presented. Furthermore, chemical sulfation and glucosylation were appli

Synthesis of chloro-substituted 6H-dibenzo[b,d]pyran-6-one natural products, graphislactone G, and palmariols A and B

A palladium-mediated intramolecular aryl–aryl coupling reaction was applied to the total synthesis of the bioactive natural products, graphislactone G (1), and palmariols A (2) and B (3), which possess an unusual chloro-subsutituent on the 6H-dibenzo[b,d]

Aminium cation-radical catalysed selective hydration of (E)-aryl enynes

The hydration of carbon-carbon triple bonds is an important and atom economic synthetic transformation. Herein, we report a mild and selective method for the catalytic Markovnikov hydration of (E)-aryl enynes to the corresponding enones, mediated through the bench-stable aminium salt, tris(4-bromophenyl)ammoniumyl hexachloroantimonate (TBPA). The chemoselective and diastereoselective method proceeds under neutral metal-free conditions, delivering excellent product yields from terminal and internal alkyne units. The synthesis of biologically important (E)-3-styrylisocoumarins, including a formal synthesis of the natural product achlisocoumarin III, demonstrates the utility of this novel transformation.

BORON-CONTAINING SMALL MOLECULES

Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.

Short and convenient synthesis of two natural phthalides by a copper(I) catalysed Sonogashira/oxacyclisation copper(I) process

Total synthesis of (±)-herbaric acid and (±)-(4- methoxybenzyl)-5,7-dimethoxyphthalide, two natural phthalide products, was achieved in 8 steps and 5 steps, respectively, starting from commercially available 3,5-dimethoxyaniline. The key step of the seque

Short and convenient synthesis of two natural phthalides by a copper(I) catalysed Sonogashira/oxacyclisation copper(I) process

Total synthesis of (±)-herbaric acid and (±)-(4-methoxybenzyl)-5,7-dimethoxyphthalide, two natural phthalide products, was achieved in 8 steps and 5 steps, respectively, starting from commercially available 3,5-dimethoxyaniline. The key step of the sequen

Formal synthesis of (R)-(+)-lasiodiplodin

A catalytic approach is reported for the enantioselective synthesis of (R)-(+)-lasiodiplodin methyl ether using asymmetric hetero allylic alkylation as the key step. Georg Thieme Verlag Stuttgart.

A chemoenzymatic and enantioselective total synthesis of the resorcylic acid lactone L-783,290, the trans-isomer of L-783,277

The structure, 5, assigned to the resorcylic acid lactone L-783,290 has been prepared for the first time and in a modular fashion using a Heck reaction to link the readily available fragments 8 and 14. Chemoenzymatic methods were used to prepare the latte

Synthesis of alternariol through an intramolecular biaryl coupling reaction using palladium reagent

The facile synthesis of altemariol was accomplished through an intramolecular biaryl coupling reaction of the phenyl benzoate derivative, which was prepared by the simple esterification of the corresponding phenol and benzoic acid using a palladium reagen

Synthesis of graphislactones A-D through a palladium-mediated biaryl coupling reaction of phenyl benzoate derivatives

The chemical synthesis of graphislactones A-D was achieved through the Pd-mediated intramolecular biaryl coupling reaction of phenyl benzoate derivatives.