16155-55-8

Usage

InChI:InChI=1/C15H13NO/c1-10-7-8-12(9-11(10)2)15-16-13-5-3-4-6-14(13)17-15/h3-9H,1-2H3

Upstream product

• 95-55-6 2-amino-phenol 
• 619-04-5 3,4-dimethylbenzoic acid 
• 164290-86-2 N-phenyl-3,4-dimethylbenzamide 
• 5973-71-7 3,4-dimethylbenzaldehyde 
• 273-53-0 benzoxazole 
• 583-71-1 4-bromo-o-xylene 
• 95-64-7 4-amino-o-xylene 

Downstream Products

• 16143-01-4 2-(3-methyl-4-trans-styryl-phenyl)-benzooxazole 
• 16256-10-3 2-[4-(trans-2-biphenyl-4-yl-vinyl)-3-methyl-phenyl]-benzooxazole 

Relevant academic research and scientific papers

Intramolecular O-arylation using nano-magnetite supported N-heterocyclic carbene-copper complex with wingtip ferrocene

Nano-magnetite supported N-heterocyclic carbene-copper complex with wingtip ferrocene has been prepared via multi-step procedure. The complex has been characterized by various analytical techniques such as fourier transform infrared (FT-IR), fourier transform Raman (FT-Raman), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), transmission electron microscopy (TEM) and vibrating sample magnetometer (VSM) analysis. The catalytic activity of the complex has been exploited in intramolecular O-arylation of o-iodoanilides under heterogeneous conditions. The complex could be successfully recycled up to twelve consecutive cycles.

Palladium-catalyzed direct C2-arylation of azoles with aromatic triazenes

A highly efficient palladium-catalyzed arylation of azoles at the C2-position using 1-aryltriazenes as aryl reagents was developed. Azoles including oxazoles, thiazoles, imidazoles, 1,3,4-oxadiazoles, and oxazolines could react with 1-aryltriazenes smoothly to generate the corresponding products in good to excellent yields, and various substitution patterns were tolerated toward the reaction.

(N-heterocyclic carbene)PdCl(N-heterocyclic carboxylate) complexes: Synthesis and catalytic activities towards arylation of benzoxazoles with aryl halides

A series of N-heterocyclic carboxylate-stabilized N-heterocyclic carbene palladium complexes have been synthesized and fully characterized. The solid-state structures indicate that each of the palladium centers is coordinated by an N-heterocyclic carbene, a chloride and a bidentate N,O-donor N-heterocyclic carboxylate ligand. The catalytic performance of the complexes was screened and the results revealed that the complexes exhibit moderate to high catalytic activities for the direct C─H bond arylation of benzoxazoles with aryl bromides.

Efficient one-pot synthesis of benzoxazole derivatives catalyzed by nickel supported silica

A simple and efficient method has been developed for the synthesis of benzoxazoles from 2-aminophenol and substituted aldehydes in the presence of a catalytic amount of nickel supported silica at room temperature.

Synthesis of 2-arylbenzoxazoles by copper-catalyzed intramolecular oxidative C-O coupling of benzanilides

(Chemical Equation Presented) No need for additives: A wide variety of functionalized 2-arylbenzoxazoles can be prepared with high functional-group tolerance and regioselectivity by a copper-catalyzed intramolecular oxidative C-O coupling of benzanilides. The catalytic cycle is completed by the regeneration of the copper catalyst using molecular oxygen as a terminal oxidant without the need for additives.