16155-60-5 Usage
Description
2-(4-methylphenyl)-5-phenyl-1,3-oxazole is a heterocyclic organic compound that features a five-membered ring with oxygen and nitrogen atoms. It is part of the oxazole class of compounds and is characterized by a phenyl group at the 5-position and a 4-methylphenyl group at the 2-position of the oxazole ring. 2-(4-methylphenyl)-5-phenyl-1,3-oxazole is known for its unique structural and electronic properties, which make it a valuable building block in the synthesis of pharmaceuticals and agrochemicals.
Uses
Used in Medicinal Chemistry:
2-(4-methylphenyl)-5-phenyl-1,3-oxazole is used as a building block for the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and electronic properties contribute to the development of new compounds with potential therapeutic applications.
Used in Antimicrobial Applications:
2-(4-methylphenyl)-5-phenyl-1,3-oxazole is used as an antimicrobial agent, leveraging its potential biological activities to combat infections caused by bacteria and other microorganisms.
Used in Anticancer Applications:
2-(4-methylphenyl)-5-phenyl-1,3-oxazole is used as an anticancer agent, where it has been studied for its ability to inhibit the growth and progression of cancer cells, making it a promising candidate for further research and development in cancer therapy.
Used in Anti-inflammatory Applications:
2-(4-methylphenyl)-5-phenyl-1,3-oxazole is used as an anti-inflammatory agent, where its potential biological activities are harnessed to reduce inflammation and alleviate symptoms associated with various inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 16155-60-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,1,5 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 16155-60:
(7*1)+(6*6)+(5*1)+(4*5)+(3*5)+(2*6)+(1*0)=95
95 % 10 = 5
So 16155-60-5 is a valid CAS Registry Number.
16155-60-5Relevant articles and documents
Divergent Conversion of N-Acyl-isoxazol-5(2 H)-ones to Oxazoles and 1,3-Oxazin-6-ones Using Photoredox Catalysis
Mei, Mingjing,Anand, Devireddy,Zhou, Lei
supporting information, p. 3548 - 3553 (2019/05/24)
The fragmentation of N-acyl-isoxazol-5-ones using visible light photoredox catalysis has been disclosed. The catalyst-controlled divergent mechanisms, namely the oxidative and reductive quenching catalytic cycle, are utilized. Various oxazoles and 1,3-oxazin-6-ones are selectively obtained from the same isoxazol-5-one skeleton under mild conditions.
Metal-free iodine(iii)-promoted synthesis of 2,5-diaryloxazoles
Yang, Xueying,Guo, Xin,Qin, Mingda,Yuan, Xinglong,Jing, Huanwang,Chen, Baohua
supporting information, p. 3104 - 3108 (2018/05/22)
A nonmetal-catalyzed oxidative cyclization to achieve 2,5-disubstituted oxazoles from inexpensive and readily available substituted chalcone, (diacetoxyiodo)benzene (PIDA) and ammonium acetate (NH4OAc) at room temperature is described. The reaction forms a variety of 2,5-diaryloxazoles in good to excellent yields with broad substrate scope under mild conditions without the requirement of ligands and additional bases.
A Heterogeneous Gold(I)-Catalyzed [2 + 2 + 1] Annulation of Terminal Alkynes, Nitriles, and Oxygen Atoms Leading to 2,5-Disubstituted Oxazoles
Yang, Weisen,Zhang, Rongli,Yi, Feiyan,Cai, Mingzhong
, p. 5204 - 5211 (2017/05/24)
The first heterogeneous gold(I)-catalyzed [2 + 2 + 1] annulation of terminal alkynes, nitriles, and oxygen atoms has been achieved by using an MCM-41-immobilized phosphine-gold(I) complex as catalyst and 8-methylquinoline N-oxide as oxidant under mild conditions, yielding a variety of 2,5-disubstituted oxazoles in good to excellent yields with broad substrate scope. The new heterogeneous gold(I) catalyst can easily be recovered by simple filtration of the reaction solution and recycled for at least eight times without significant loss of activity.
