1617-68-1

Basic information

• Product Name: LUPEOL ACETATE
• Synonyms: LUPEOL ACETATE;3-O-Acetyllupeol;Lup-20(29)-en-3beta-ol, acetate;Lup-20(29)-en-3-ol, acetate, (3beta)-;Lup-20(29)-en-3-yl acetate;Lupenyl acetate;Lupeyl acetate;LUPEOL ACETATE (REAGENT / STANDARD GRADE)
• CAS NO: 1617-68-1
• Molecular Formula: C₃₂H₅₂O₂
• Molecular Weight: 468.75
• EINECS: 216-575-8
• Product Categories: Tri-Terpenoids
• Mol File: 1617-68-1.mol
• Article Data: 31

Chemical Properties

• Melting Point: 218°C
• Boiling Point: 502.7°Cat760mmHg
• Flash Point: 254.7°C
• Appearance: /
• Density: 1.01g/cm³
• CAS DataBase Reference: LUPEOL ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: LUPEOL ACETATE(1617-68-1)
• EPA Substance Registry System: LUPEOL ACETATE(1617-68-1)

Safety Data

• Hazardous Substances Data: 1617-68-1(Hazardous Substances Data)

Usage

Uses

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Upstream product

• 545-47-1 lupenol 
• 71-41-0 pentan-1-ol 
• 20555-16-2 lup-20(30)-en-3β-ol-29-al acetate 
• 1941-84-0 sodium pentanolate 
• 7803-57-8 hydrazine hydrate 
• 3608-09-1 18α-oleanane-3β,19α-diol 
• 10025-87-3 trichlorophosphate 
• 27570-21-4 3-O-acetylbetulinal 
• 108-24-7 acetic anhydride 
• 2873-29-2 D-glucal triacetate 
• 1617-70-5 lupenone 
• 501124-71-6 3-acetoxy-28-tert-butyldimethylsiloxybetulin 
• 501124-70-5 (3β)-28-[(dimethylethyl)dimethylsilyloxy]lup-20(29)-en-3-ol 
• 473-98-3 betulin 

Downstream Products

• 50-00-0 formaldehyd 
• 55870-41-2 3β-acetoxy-30-nor-lupan-20-one 
• 51361-60-5 olean-13(18)-en-3β-yl acetate 
• 1030385-77-3 3β-O-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-lup-20(29)-ene 

Related news

LUPEOL ACETATE (cas 1617-68-1) ameliorates collagen-induced arthritis and osteoclastogenesis of mice through improvement of microenvironment07/19/2019

Lupeol has been shown with anti-inflammation and antitumor capability, however, the poor bioavailability limiting its applications in living subjects. Lupeol acetate (LA), a derivative of lupeol, shows similar biological activities as lupeol but with better bioavailability. Here RAW 264.7 cells ...detailed

Relevant articles and documents

Design and synthesis of new lupeol derivatives and their α-glucosidase inhibitory and cytotoxic activities

A series of lupeol derivatives 2, 2a-2f, 2a-2h, 3a-3e, and 4a-4b were designed, synthesised and evaluated for their α-glucosidase inhibitory and cytotoxic activities. Among synthetic derivatives, lupeol analogues 2b and 2e containing a benzylidene chain exhibited the best activity against α-glucosidase and superior to the positive agent with the IC50 values of 29.4 ± 1.33 and 20.1 ± 0.91 μM, respectively. Lupeol analogues 2d and 3a showed weak cytotoxicity against K562 cell line with the IC50 values of 76.6 ± 2.40 and 94.4 ± 1.51 μM, respectively.

Improved isolation of betulin and lupeol from birch bark and oxidation of their acetylated derivatives with chromyl chloride

Abstract: An improved method of isolation of betulin and lupeol from birch bark is developed and reported. The method afforded triterpenes with purity of 98.2% (betulin) and 96.3% (lupeol), respectively. Chromyl chloride was also investigated as an oxidating agent of O-acetylated betulin and lupeol. The transformation of isopropenyl moiety to aldehyde group was observed.

Practical Synthesis of α-Amyrin, β-Amyrin, and Lupeol: The Potential Natural Inhibitors of Human Oxidosqualene Cyclase

A practical synthesis of α-amyrin (1), β-amyrin (2), and lupeol (3) was accomplished in total yields of 32, 42, and 40% starting from easily available ursolic acid (4), oleanolic acid (5), and betulin (6), respectively. Remarkably, these three natural pentacyclic triterpenes exhibited potential inhibitory activity against human oxidosqualene cyclase.