16180-96-4

Basic information

• Product Name: 2-acetamidoethyl acetate
• Synonyms: 2-acetamidoethyl acetate;N-[2-(Acetyloxy)ethyl]acetamide;Acetamide, N-(2-(acetyloxy)ethyl)-;Einecs 240-317-3;N-(2-ACETOXYETHYL)ACETAMIDE
• CAS NO: 16180-96-4
• Molecular Formula: C₆H₁₁NO₃
• Molecular Weight: 145.15644
• EINECS: 240-317-3
• Mol File: 16180-96-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 301.1°Cat760mmHg
• Flash Point: 135.9°C
• Appearance: /
• Density: 1.059g/cm³
• Vapor Pressure: 0.00108mmHg at 25°C
• Refractive Index: 1.428
• CAS DataBase Reference: 2-acetamidoethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-acetamidoethyl acetate(16180-96-4)
• EPA Substance Registry System: 2-acetamidoethyl acetate(16180-96-4)

Safety Data

• Hazardous Substances Data: 16180-96-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H11NO3/c1-5(8)7-3-4-10-6(2)9/h3-4H2,1-2H3,(H,7,8)

Upstream product

• 98553-10-7 1-acetoxy-2-acetylamino-1-ethylsulfanyl-ethane 
• 142-26-7 2-acetylaminoethanol 
• 108-24-7 acetic anhydride 
• 141-43-5 ethanolamine 
• 5804-92-2 2-(trimethylsilyloxy)ethanamine 
• 19220-93-0 pentafluorophenyl acetate 
• 463-51-4 Ketene 
• 98-59-9 p-toluenesulfonyl chloride 
• 141-78-6 ethyl acetate 
• 17101-83-6 N-<2-Chlor-ethyl>-diacetyl-amin 
• 127-09-3 sodium acetate 

Relevant articles and documents

Method using amide ester to prepare diamine derivative

The invention provides a method using amide ester to prepare a diamine derivative. The method is characterized in that ester groups in amide esters containing both amide and ester functional groups are substituted to prepare the diamine derivative, and one of the diamine groups of the diamine derivative is carboxylic acid amide reserved from the amide ester raw materials. The method is cheap in raw material, easy in raw material obtaining, low in catalyst use amount, simple in reaction conditions and high in product stereoselectivity.

Sulfonylation-induced N-to O -Acetyl migration in 2-acetamidoethanol derivatives

The first example of sulfonylation-induced N- to O-acetyl migration of 2-acetamidoethanol derivatives is described. This type of reaction could happen with any 2-acetamidoethanol derivatives under typical sulfonylation conditions (TsCl or MsCl, pyridine) and might be a common side reaction of significance. Furthermore, the results reveal that 2-acetamidoethanol derivatives with a sterically encumbered hydroxyl group result in the migration products in high yields. The mechanism of the migration reaction is discussed.

Acetyl transfer reactions on AlPO4-Al2O3

An efficient acetylation of alcohols and aliphatic amines promoted by the AlPO4-Al2O3/ethyl acetate system is described.The solid catalist acts, at least in part, as the acetyl carrier.