161987-82-2

Basic information

• Product Name: ((3aR,6S,6aR)-6-Benzyloxymethyl-5-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-methanol
• Synonyms: ((3aR,6S,6aR)-6-Benzyloxymethyl-5-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-methanol
• CAS NO: 161987-82-2
• Molecular Weight: 324.374
• Mol File: 161987-82-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: ((3aR,6S,6aR)-6-Benzyloxymethyl-5-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: ((3aR,6S,6aR)-6-Benzyloxymethyl-5-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-methanol(161987-82-2)
• EPA Substance Registry System: ((3aR,6S,6aR)-6-Benzyloxymethyl-5-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-methanol(161987-82-2)

Safety Data

• Hazardous Substances Data: 161987-82-2(Hazardous Substances Data)

Upstream product

• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 2847-00-9 1,2:5,6-di-O-isopropylidene-α-D-hexofuran-3-ulose 
• 21665-16-7 O¹,O²;O⁵,O⁶-diisopropylidene-3-methylene-α-D-ribo-3-deoxy-hexofuranose 
• 69832-48-0 ((3aR,5S,6R,6aR)-tetrahydro-2,2-dimethyl-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)furo[2,3-d][1,3]dioxol-6-yl)methanol 
• 50-00-0 formaldehyd 
• 149207-10-3 (3aR,5S,6R,6aR)-6-Benzyloxymethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole-5-carbaldehyde 
• 85315-68-0 3-C-(benzyloxymethyl)-3-deoxy-1,2-O-isopropylidene-α-D-allofuranose 
• 85315-67-9 3-C-(benzyloxymethyl)-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 

Downstream Products

• 629613-71-4 Methanesulfonic acid (3aR,6S,6aR)-6-benzyloxymethyl-5-methanesulfonyloxymethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl ester 
• 377079-33-9 Toluene-4-sulfonic acid (2S,3S,4R,5R)-2,3-bis-benzyloxymethyl-4-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 
• 377079-34-0 Toluene-4-sulfonic acid (2S,3S,4R,5R)-2,3-bis-benzyloxymethyl-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-hydroxy-tetrahydro-furan-2-ylmethyl ester 
• 377079-29-3 Acetic acid (2S,3S,4R,5R)-4-acetoxy-2,3-bis-benzyloxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 
• 377079-30-6 Acetic acid (2S,3S,4R,5R)-4-acetoxy-2,3-bis-benzyloxymethyl-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 
• 377079-31-7 1-((2R,3R,4S,5R)-4,5-Bis-benzyloxymethyl-3-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione 
• 377079-32-8 1-((2R,3R,4S,5R)-4,5-Bis-benzyloxymethyl-3-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione 
• 377079-35-1 1-((1S,3R,4R,7S)-1,7-Bis-benzyloxymethyl-2,5-dioxa-bicyclo[2.2.1]hept-3-yl)-5-methyl-1H-pyrimidine-2,4-dione 
• 377079-37-3 1-((1S,3R,4R,7S)-1,7-Bis-benzyloxymethyl-2,5-dioxa-bicyclo[2.2.1]hept-3-yl)-1H-pyrimidine-2,4-dione 
• 377079-28-2 Acetic acid (2S,3S,4R)-4,5-diacetoxy-2,3-bis-benzyloxymethyl-tetrahydro-furan-2-ylmethyl ester 
• 377079-27-1 Acetic acid (3aR,5S,6S,6aR)-5,6-bis-benzyloxymethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl ester 
• 629613-67-8 1-[6a-(tert-butyl-diphenyl-silanyloxymethyl)-3-hydroxy-hexahydro-furo[3,4-b]furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 629613-68-9 1-[6a-(tert-butyl-diphenyl-silanyloxymethyl)-hexahydro-furo[3,4-b]furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 161987-83-3 (3aR,6S,6aR)-5,5,6-Tris-benzyloxymethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole 

Relevant articles and documents

Synthesis and biological evaluation of pyrimidine nucleosides fused with 3′,4′-tetrahydrofuran ring

Pyrimidine nucleosides fused with 3′,4′-tetrahydrofuran ring were synthesized, starting from 1,2;5,6-di-O-isopropylidene-D-glucose and assayed for antiviral activities. Thymine analogue 1 and its corresponding 2′-deoxy analogue 3 exhibited high cytotoxici

Synthesis of novel 3′-deoxy-3′-C-hydroxymethyl nucleosides with conformationally rigid sugar moiety as potential antiviral agents

Based on the fact that the ring expanded 3′-C-hydroxymethyl analogue of oxetanocin A exhibited potent antiviral activity, two types of conformationally rigid 3′-C-hydroxymethyl derivatives in which 2′-hydroxyl group is linked to the 4′-position or to the 6′-position were synthesized starting from 1,2;5,6-di-O-isopropylidene-D-glucose, respectively.