1620-68-4

Basic information

• Product Name: 2,6-BIS[(2-HYDROXY-5-METHYLPHENYL)METHYL]-4-METHYLPHENOL
• Synonyms: 2,6-bis[(2-hydroxy-5-methylphenyl)methyl]-4-methyl-pheno;bishydroxymethylphenylmethylmethylphenol;2,6-BIS[(2-HYDROXY-5-METHYLPHENYL)METHYL]-4-METHYLPHENOL;2,6-BIS(P-CRESOL-2-YLMETHYL)-P-CRESOL;2,6-bis[(2-hydroxy-5-methylphenyl)methyl]p-cresol;2,6-BIS(2-HYDROXY-5-METHYLBENZYL)-4-METHYLPHENOL;2,6-BIS[(2-HYDROXY-5-METHYLPHENYL)METHYL]-4-METHYLPHENOL 98+%;Antioxidant 80
• CAS NO: 1620-68-4
• Molecular Formula: C₂₃H₂₄O₃
• Molecular Weight: 348.43
• EINECS: 216-587-3
• Mol File: 1620-68-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 214 °C
• Boiling Point: 533.7°Cat760mmHg
• Flash Point: 241.9°C
• Appearance: /
• Density: 1.191g/cm³
• Vapor Pressure: 5.28E-12mmHg at 25°C
• Refractive Index: 1.637
• PKA: 9.98±0.43(Predicted)
• CAS DataBase Reference: 2,6-BIS[(2-HYDROXY-5-METHYLPHENYL)METHYL]-4-METHYLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-BIS[(2-HYDROXY-5-METHYLPHENYL)METHYL]-4-METHYLPHENOL(1620-68-4)
• EPA Substance Registry System: 2,6-BIS[(2-HYDROXY-5-METHYLPHENYL)METHYL]-4-METHYLPHENOL(1620-68-4)

Safety Data

• Hazardous Substances Data: 1620-68-4(Hazardous Substances Data)

Usage

General Description

2,6-BIS[(2-HYDROXY-5-METHYLPHENYL)METHYL]-4-METHYLPHENOL is a chemical compound with antioxidant properties. It is a phenolic compound with two hydroxy groups and a methyl group attached to a benzene ring. 2,6-BIS[(2-HYDROXY-5-METHYLPHENYL)METHYL]-4-METHYLPHENOL is often used in the production of synthetic antioxidants for food products, such as stabilizing agents for fats and oils. It is also utilized in the production of polymers and plastics as a stabilizer against degradation caused by heat and light. Additionally, this chemical has potential benefits in the field of medical research due to its antioxidant properties.

InChI:InChI=1/C23H24O3/c1-14-4-6-21(24)17(8-14)12-19-10-16(3)11-20(23(19)26)13-18-9-15(2)5-7-22(18)25/h4-11,24-26H,12-13H2,1-3H3

Upstream product

• 50-00-0 formaldehyd 
• 106-44-5 p-cresol 
• 5862-32-8 2,6-bis(chloromethyl)-4-methylphenol 
• 126742-55-0 2-Hydroxy-5-methyl-1.3-bis-thiocyanatomethyl-benzol 
• 80678-92-8 3-(5-methylsalicyl)-5-methylsalicyl alcohol 
• 7647-01-0 hydrogenchloride 
• 91-04-3 2,6-bis(hydroxymethyl)-4-methylphenol 
• 64-17-5 ethanol 
• 7732-18-5 water 
• 67-56-1 methanol 
• 409317-20-0 2-hydroxy-5-methyl-3-thiocyanatomethyl-benzyl alcohol 
• 3236-63-3 2,2'-methylenebis(4-methylphenol) 
• 2409-55-4 2-tert-Butyl-4-methylphenol 
• 90-68-6 2,6-bis[[3-(1,1-dimethylethyl)-2-hydroxy-5-methylphenyl]methyl]-4-methyl-phenol 

Downstream Products

• 106-44-5 p-cresol 
• 527-60-6 Mesitol 
• 105-67-9 2,4-Xylenol 
• 518361-66-5 [4-methyl-2,6-bis-(5-methyl-2-pentafluorophenyloxycarbonylmethoxy-benzyl)-phenoxy]-acetic acid pentafluorophenyl ester 
• 518361-60-9 [2,6-bis-(2-carboxymethoxy-5-methyl-benzyl)-4-methyl-phenoxy]-acetic acid 
• 518361-57-4 [2,6-bis-(2-ethoxycarbonylmethoxy-5-methyl-benzyl)-4-methyl-phenoxy]-acetic acid ethyl ester 
• 22247-59-2 3-[3-[3-(hydroxymethyl)-5-methylsalicyl]-5-methylsalicyl]-2-hydroxy-5-methylbenzylalcohol 
• 245058-02-0 6-diethylamino-4-(2-hydroxy-5-methylbenzyl)-2,10-dimethyldibenzo<1,3,2>-dioxaphosphacane 
• 103442-38-2 2-(2,4-Dinitro-phenoxy)-1,3-bis-[2-(2,4-dinitro-phenoxy)-5-methyl-benzyl]-5-methyl-benzene 
• 54637-31-9 2-{2,6-Bis-[2-(2-hydroxy-ethoxy)-5-methyl-benzyl]-4-methyl-phenoxy}-ethanol 
• 54637-29-5 2,6-Bis-[2-(2-hydroxy-ethoxy)-5-methyl-benzyl]-4-methyl-phenol 
• 54637-27-3 2-[2-(2-Hydroxy-ethoxy)-5-methyl-benzyl]-6-(2-hydroxy-5-methyl-benzyl)-4-methyl-phenol 
• 129788-52-9 C₃₈H₃₄O₆ 

Relevant articles and documents

Effect of SnO2/Al2O3 ratio of Si-based MFI on its acidity and hydrophobicity: Application in selective hydroxyalkylation of p-cresol

Silica based MFI type molecular sieves with various SnO2/Al 2O3 ratios were synthesized from gels having molar compositions SiO2:xSnO2:yAl2O 3:0.23(TPA)2O:35H2O where 0 ≤ x ≤ 0.02 and 0 ≤ y ≤ 0.01. Recyclable, Al-free Sn-MFI catalyst showed 31% conversion of formaldehyde with 100% selectivity to 2,2′-methylenebis(4- methylphenol) in hydroxyalkylation of p-cresol with formaldehyde on account of moderate acidity and higher hydrophobicity.

Solvent-free synthesis of trisphenols as starting precursors for the synthesis of calix[4]arenes using sulfonated multi-walled carbon nanotubes

The condensation of phenol derivatives (12 substrates) with 2,6-bis(hydroxymethyl)phenols (BMP) (6 examples) is reported using sulfonated multi-walled carbon nanotubes (SO3H@MWCNTs) under solvent-free conditions as starting precursors for the synthesis of macrocyclic molecules of calix[4]arenes. The new protocol provides a series of trisphenol derivatives (21 examples) in high yields (up to 94%) and relatively short reaction times (15-120 min). Also, direct synthesis of calix[4]arenes from different trisphenols by use of the catalyst was reported (5 examples). Furthermore, the synthesized calix[4]arene was obtained using a one-pot method from simple and easily available starting materials such as p-cresol for the synthesis of 5,11,17,23-tetramethylcalix[4]arene-25,26,27,28-tetraol. Also, in this process SO3H@MWCNTs can be reused for seven runs with almost consistent efficiency and can be recovered by easy filtration.

The reaction of hexaalkylphosphorous triamides with oligophenols

Hexaalkylphosphorous triamides form in good yields 6-dialkylamino-12H-dibenzo[d.g] [1,3,2]dioxaphosphocins 2a-i in the reaction with oligophenols 1a-i. Heating the sterical hindered compounds 2a-f up to 315°C leads to the corresponding bicyclic phosphites 3a-d while the non-hindered phosphocins 2g-i react in refluxing xylene to give phosphites 3e-g. The phosphocin 2i formed another phosphocin 2i* during heating to 90°C in THF by "wandering" of the phosphorus moiety. The bicyclic phosphites 3h and 3i were prepared starting from tetraphenol 1h and pentaphenol 1i by reaction with hexaethylphosphorous triamide in refluxing xylene. The diphosphorylated triphenol 4 and tetraphenol 5 are formed in the reaction of the corresponding phenols with 2 eq. of hexaalkylphosphorous triamide.